Use of analgesic Novigan for the treatment of tension-type headache in patients with concomitant somatic pathology


Cite item

Full Text

Abstract

The article is dedicated to the features of tension-type headache; data for the place of nonsteroidal anti-inflammatory drugs (NSAIDs) in treatment of pain management are presented. The possibilities of use of the new combined analgesics, such as drug Novigan, are discussed. Novigan is a combination of NSAID ibuprofen (400 mg), pitofenone hydrochloride, papaverin-like peripheral action spasmolytic, and fenpiverinium bromide, cholinolytic with central and peripheral actions. The results of randomized open comparative study aimed to evaluation of efficacy and safety of Novigan and ibuprofen (MIG 400) in 45 patients with tension-type headache and concomitant somatic pathology are presented. It was shown that Novigan is an effective drug for the treatment of cephalgic syndrome of musculosceletal origin that affects the basic mechanisms of its development. Novigan is superior to MIG 400 in the rate of development of analgesic effect, which is obviously due to the presence of spasmolytic component and pharmacokinetic characteristics of the drug.

References

  1. Боконжич Р. Головная боль. М., 1984. C. 312.
  2. Кукушкин М.А., Хитров Н.К. Общая патология боли (Руководство для врачей). М., 2004. C. 140.
  3. Машфорд М.Л., Кохен М.Л. и соавт. Боль и аналгезия: Справочник практикующего врача. М., 2004. C. 488.
  4. Насонов Е.Л. Нестероидные противовоспалительные препараты (Перспективы применения в медицине). М., 2000.
  5. Насонов Е.Л. Каратеев А.Е. Поражение желудка, связанное с приемом нестероидных противовоспалительных препаратов (часть I) // Клиническая медицина 2000. № 3. С. 410.
  6. Насонов Е.Л., Каратеев А.Е. Гастропатия, связанная с приемом нестероидных противовоспалительных препаратов (часть II) // Клиническая медицина 2000. № 4. С. 49.
  7. Филатова Е.Г., Соловьева А.Д., Данилов А.Б Лечение головной боли напряжения // Журнал неврология и психиатрия 1996. № 4. С. 21--25.
  8. Соловьева А.Д., Филатова Е.Г., Вознесенская Т.Г, Канавец Е.В. Клиника, диагностика и терапия головных болей у больных с гипоталамическим синдромом // Журнал неврологии и психиатрии 1996. № 4. С. 21-25.
  9. Herrmann WM, Hiersemenzel R, Aigner M, et al. Long-term tolerance of flupirtine. Open multicenter study over one year. Fortschr Med 1993;111(15):266-70.
  10. McMahon G, Arndt W, Newton J, et al. Clinical experience of flupirtine in the US. Postgrad Med J 1987;63:81-85.
  11. Mdntyselka P, Kumpusalo E, Ahonen R, et al. Pain as a reason to visit the doctor: a study in Finnish primary health care. Pain 200;89(2-3):175-80.
  12. Coward DM. Pharmacology and mechanisms of action of tizanidine (Sirdalud). The Parthenon Publishing Group. 1989:131-40
  13. Berry H, Hutchinson DR. Tizanidine and ibuprofen in acute low-back pain: Results of a double-blind multicentre study in general practice. J Intern Med Res 1988;16:83-91.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2010 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies