Формирование микробиоты младенца в зависимости от характера вскармливания
- Авторы: Захарова И.Н.1, Сугян Н.Г.1,2, Оробинская Я.В.1,2
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Учреждения:
- ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России
- ГБУЗ МО «Химкинская больница»
- Выпуск: № 2 (2024)
- Страницы: 106-111
- Раздел: Статьи
- URL: https://pediatria.orscience.ru/2658-6630/article/view/635395
- DOI: https://doi.org/10.26442/26586630.2024.2.202939
- ID: 635395
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Аннотация
Олигосахариды грудного молока (ОГМ) представляют собой короткие полимеры простых сахаров, которые в высоких концентрациях присутствуют в ГМ женщины. Их содержание динамично меняется с течением времени. На уровень ОГМ особое влияние оказывают генетические факторы, а также имеют значение продолжительность лактации, особенности окружающей среды. ОГМ могут поддерживать развитие иммунной системы и обеспечивать защиту от инфекционных заболеваний непосредственно через взаимодействие эпителиальных клеток кишечника или косвенно через модуляцию кишечной микробиоты, включая стимуляцию роста Bifidobacterium. Клинические данные свидетельствуют о том, что добавление ОГМ в детские молочные смеси способствует нормальному росту новорожденного и приносит пользу его здоровью. Добавление 1 или 2 ОГМ в молочные смеси безопасно и приближает их состав к ГМ, позволяя ребенку гармонично развиваться.
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Об авторах
Ирина Николаевна Захарова
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России
Автор, ответственный за переписку.
Email: zakharova-rmapo@yandex.ru
ORCID iD: 0000-0003-4200-4598
д-р мед. наук, проф., зав. каф. педиатрии им. акад. Г.Н. Сперанского ФГБОУ ДПО РМАНПО, засл. врач РФ
Россия, МоскваНарине Григорьевна Сугян
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России; ГБУЗ МО «Химкинская больница»
Email: zakharova-rmapo@yandex.ru
ORCID iD: 0000-0002-2861-5619
канд. мед. наук, доц. каф. педиатрии им. акад. Г.Н. Сперанского ФГБОУ ДПО РМАНПО, зам. глав. врача ГБУЗ МО ХБ
Россия, Москва; ХимкиЯна Владимировна Оробинская
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России; ГБУЗ МО «Химкинская больница»
Email: zakharova-rmapo@yandex.ru
ORCID iD: 0009-0005-2121-4010
аспирант каф. педиатрии им. акад. Г.Н. Сперанского ФГБОУ ДПО РМАНПО, поликлиника «Мама и малыш» ГБУЗ МО ХБ
Россия, Москва; ХимкиСписок литературы
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