Формирование микробиоты младенца в зависимости от характера вскармливания

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Олигосахариды грудного молока (ОГМ) представляют собой короткие полимеры простых сахаров, которые в высоких концентрациях присутствуют в ГМ женщины. Их содержание динамично меняется с течением времени. На уровень ОГМ особое влияние оказывают генетические факторы, а также имеют значение продолжительность лактации, особенности окружающей среды. ОГМ могут поддерживать развитие иммунной системы и обеспечивать защиту от инфекционных заболеваний непосредственно через взаимодействие эпителиальных клеток кишечника или косвенно через модуляцию кишечной микробиоты, включая стимуляцию роста Bifidobacterium. Клинические данные свидетельствуют о том, что добавление ОГМ в детские молочные смеси способствует нормальному росту новорожденного и приносит пользу его здоровью. Добавление 1 или 2 ОГМ в молочные смеси безопасно и приближает их состав к ГМ, позволяя ребенку гармонично развиваться.

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Об авторах

Ирина Николаевна Захарова

ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России

Автор, ответственный за переписку.
Email: zakharova-rmapo@yandex.ru
ORCID iD: 0000-0003-4200-4598

д-р мед. наук, проф., зав. каф. педиатрии им. акад. Г.Н. Сперанского ФГБОУ ДПО РМАНПО, засл. врач РФ

Россия, Москва

Нарине Григорьевна Сугян

ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России; ГБУЗ МО «Химкинская больница»

Email: zakharova-rmapo@yandex.ru
ORCID iD: 0000-0002-2861-5619

канд. мед. наук, доц. каф. педиатрии им. акад. Г.Н. Сперанского ФГБОУ ДПО РМАНПО, зам. глав. врача ГБУЗ МО ХБ

Россия, Москва; Химки

Яна Владимировна Оробинская

ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России; ГБУЗ МО «Химкинская больница»

Email: zakharova-rmapo@yandex.ru
ORCID iD: 0009-0005-2121-4010

аспирант каф. педиатрии им. акад. Г.Н. Сперанского ФГБОУ ДПО РМАНПО, поликлиника «Мама и малыш» ГБУЗ МО ХБ

Россия, Москва; Химки

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