Pediatrics. Consilium MedicumPediatrics. Consilium MedicumПедиатрия. Consilium Medicum2658-66302658-6622Consilium Medicum10954010.26442/26586630.2022.2.201745ArticlesСтатьиReview ArticleInnovations in the dietary therapy of cow's milk protein allergy: enrichment of highly hydrolyzed infant formulas with human milk oligosaccharides: A reviewИнновации диетотерапии аллергии к белкам коровьего молока: обогащение высокогидролизованных смесей олигосахаридами грудного молокаhttps://orcid.org/0000-0003-4200-4598ZakharovaIrina N.ЗахароваИрина Николаевна
Russian Federation

D. Sci. (Med.), Prof., Russian Medical Academy of Continuous Professional Education

д-р мед. наук, проф., зав. каф. педиатрии им. акад. Г.Н. Сперанского ФГБОУ ДПО РМАНПО, засл. врач России

zakharova-rmapo@yandex.ruhttps://orcid.org/0000-0003-3181-9601OsmanovIsmail M.ОсмановИсмаил Магомедович
Russian Federation

D. Sci. (Med.), Prof., Bashlyaeva Children's City Clinical Hospital, Pirogov Russian National Research Medical University

д-р мед. наук, проф., глав. врач ГБУЗ «ДГКБ им. З.А. Башляевой», дир. Университетской педиатрической клиники ФГАОУ ВО «РНИМУ им. Н.И. Пирогова», гл. внештат. специалист педиатр Департамента здравоохранения г. Москвы, засл. врач России, засл. врач Москвы

zakharova-rmapo@yandex.ruhttps://orcid.org/0000-0002-2847-6268BerezhnayaIrina V.БережнаяИрина Владимировна
Russian Federation

Cand. Sci. (Med.), Russian Medical Academy of Continuous Professional Education

канд. мед. наук, доц. каф. педиатрии им. акад. Г.Н. Сперанского ФГБОУ ДПО РМАНПО

berezhnaya-irina26@yandex.ruhttps://orcid.org/0000-0002-1593-0732DmitrievaDiana K.ДмитриеваДиана Кирилловна
Russian Federation

Graduate Student, Russian Medical Academy of Continuous Professional Education

аспирант каф. педиатрии им. акад. Г.Н. Сперанского ФГБОУ ДПО РМАНПО

dmitrievadi@mail.ruSkorobogatovaEkaterina V.СкоробогатоваЕкатерина Владимировна
Russian Federation

Cand. Sci. (Med.), Bashlyaeva Children's City Clinical Hospital

канд. мед. наук, зав. педиатрическим отд-нием ГБУЗ «ДГКБ им. З.А. Башляевой»

dgkb-bashlyaevoy@zdrav.mos.ruGostiukhinaAnastasiia D.ГостюхинаАнастасия Дмитриевна
Russian Federation

Medical Resident, Russian Medical Academy of Continuous Professional Education

врач-ординатор каф. педиатрии им. акад. Г.Н. Сперанского ФГБОУ ДПО РМАНПО

zakharova-rmapo@yandex.ruRussian Medical Academy of Continuous Professional EducationФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава РоссииBashlyaeva Children's City Clinical HospitalГБУЗ «Детская городская клиническая больница им. З.А. Башляевой» Департамента здравоохранения г. МосквыPirogov Russian National Research Medical UniversityФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России30072022212212729072022Copyright ©; 2022, Consilium MedicumCopyright ©; 2022, ООО "Консилиум Медикум"2022Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://pediatria.orscience.ru/2658-6630/article/view/109540

The prevalence of food allergies has been increasing over the past 30 years. One of the most common causes of food allergies in children today is an allergy to cow's milk proteins (ACMP). Diagnosis of the ACMP can often be difficult, given the pathomorphism of the manifestations. Both in the diagnosis and in the treatment of children with manifestations of ACMP, a rejection of any dairy products and, consequently, the selection of a complete substitute to maintain a diet adequate in composition, action and caloric content is required. The use of highly hydrolyzed and amino acid formulas in the nutrition of children with ACMP is preferable, given the current opportunities that bring adapted formulas closer to the composition of breast milk, using breast milk oligosaccharides to support the development of early oral tolerance.

Одной из самых частых причин развития пищевой аллергии у детей в настоящее время являются белки коровьего молока (БКМ). Диагностика аллергии к БКМ (АБКМ) может быть затруднена, учитывая патоморфизм клинических проявлений, а также как IgE-, так и не-IgE-опосредованные варианты патологии. При выборе диетотерапии для детей с симптомами АБКМ требуется полный отказ от любых молочных продуктов и, следовательно, подбор полноценной замены для поддержания адекватного по составу, действию и калорийности питания рациона. Использование высокогидролизованных и аминокислотных смесей в питании детей с АБКМ является предпочтительным, поскольку современные гидролизованные смеси высокоэффективны, а добавление в них олигосахаридов грудного молока оказывает дополнительное влияние на формирование оральной толерантности.

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