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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pediatrics. Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Pediatrics. Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Педиатрия. Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2658-6630</issn><issn publication-format="electronic">2658-6622</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">636985</article-id><article-id pub-id-type="doi">10.26442/26586630.2024.3.202930</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The positive effect of ω-3 polyunsaturated fatty acid supplementation on the cognitive function of children and adolescents with lipid metabolism disorders</article-title><trans-title-group xml:lang="ru"><trans-title>Положительное влияние дотации ω-3 полиненасыщенных жирных кислот на когнитивные функции детей и подростков с нарушениями липидного обмена</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4200-4598</contrib-id><name-alternatives><name xml:lang="en"><surname>Zakharova</surname><given-names>Irina N.</given-names></name><name xml:lang="ru"><surname>Захарова</surname><given-names>Ирина Николаевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>D. Sci. (Med.), Prof.</p></bio><bio xml:lang="ru"><p>-р мед. наук, проф., зав. каф. педиатрии им. акад. Г.Н. Сперанского ФГБОУ ДПО РМАНПО, засл. врач РФ</p></bio><email>zakharova-rmapo@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Korchagina</surname><given-names>Iuliya V.</given-names></name><name xml:lang="ru"><surname>Корчагина</surname><given-names>Юлия Владиславовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Resident</p></bio><bio xml:lang="ru"><p>ординатор каф. педиатрии им. акад. Г.Н. Сперанского</p></bio><email>zakharova-rmapo@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0058-3803</contrib-id><name-alternatives><name xml:lang="en"><surname>Pshenichnikova</surname><given-names>Irina I.</given-names></name><name xml:lang="ru"><surname>Пшеничникова</surname><given-names>Ирина Игоревна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>канд. мед. наук; доц. каф. педиатрии им. акад. Г.Н. Сперанского</p></bio><email>shenichnikovaII@rmapo.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Russian Medical Academy of Continuous Professional Education</institution></aff><aff><institution xml:lang="ru">ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-11-01" publication-format="electronic"><day>01</day><month>11</month><year>2024</year></pub-date><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>260</fpage><lpage>265</lpage><history><date date-type="received" iso-8601-date="2024-10-13"><day>13</day><month>10</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-10-13"><day>13</day><month>10</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://pediatria.orscience.ru/2658-6630/article/view/636985">https://pediatria.orscience.ru/2658-6630/article/view/636985</self-uri><abstract xml:lang="en"><p><bold>Aim</bold>. To study the effect of ω-3 polyunsaturated fatty acids (PUFAs) on the cognitive functions of children with lipid metabolism disorders of different ages.</p> <p><bold>Materials and methods</bold>. The study included 87 children aged 6 to 17 years who had not previously received ω-3 PUFA supplements. All subjects were tested twice, with an interval of 6 months, to determine the ω-3 erythrocyte index by gas chromatography-mass spectrometry and to study attention span and focusing using the correction task method (Bourdon test). The cohort was randomly divided into two groups: the main group, which included 60 children who received the ω-3 supplements, and the control group, which included 27 children who did not receive any nutritional supplements.</p> <p><bold>Results</bold>. In children of the main group, after receiving the Norwegian fish oil NFO® at 1000 mg for 6 months, an increase in the erythrocyte ω-3 index was observed, while in the control group, it did not change significantly. A statistically significant correlation was found between the adequacy of ω-3 PUFA and the attention span and focusing.</p> <p><bold>Conclusion</bold>. The results of the study showed the effectiveness of ω-3 PUFA supplementation at 1000 mg/day for 6 months and confirmed the positive effect of ω-3 PUFA on the cognitive sphere of children and adolescents. High-quality food supplements with ω-3 PUFAs at 1000 mg/day can be recommended to develop intellection, memory, and attention span and focus in children and adolescents.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель</bold>. Изучить влияние ω-3 полиненасыщенных жирных кислот (ПНЖК) на когнитивные функции детей с нарушениями липидного обмена разного возраста.</p> <p><bold>Материалы и методы</bold>. Обследованы 87 детей в возрасте от 6 до 17 лет, ранее не получавших добавок ω-3 ПНЖК. Всем испытуемым дважды с интервалом 6 мес выполнено определение ω-3 эритроцитарного индекса методом газовой хроматографии-масс-спектрометрии, а также проведено исследование устойчивости и концентрации внимания с использованием методики «Корректурная проба» (тест Бурдона). Случайным образом когорта разделена на 2 группы: основную, куда вошли 60 детей, получавших дотацию ω-3, и контрольную, которая включала 27 детей, не получавших никакие пищевые добавки.</p> <p><bold>Результаты</bold>. У детей основной группы после дотации норвежского рыбьего жира NFO® в дозе 1000 мг в течение 6 мес отмечено увеличение ω-3 индекса эритроцитов, в то время как в группе контроля данный показатель существенно не изменился. Получена статистически значимая взаимосвязь между обеспеченностью ω-3 ПНЖК и уровнями концентрации и устойчивости внимания.</p> <p><bold>Заключение</bold>. Результаты проведенного исследования показали эффективность дотации ω-3 ПНЖК в дозе 1000 мг/сут в течение 6 мес, а также подтвердили данные о положительном влиянии ω-3 ПНЖК на состояние когнитивной сферы детей и подростков. Применение качественных пищевых добавок ω-3 ПНЖК в дозе 1000 мг/сут может быть рекомендовано для развития мышления, памяти, концентрации и устойчивости внимания в детском и подростковом возрасте.</p></trans-abstract><kwd-group xml:lang="en"><kwd>ω-3 polyunsaturated fatty acids</kwd><kwd>ω-3 erythrocyte index</kwd><kwd>cognitive function</kwd><kwd>attention span</kwd><kwd>attention concentration</kwd><kwd>children</kwd><kwd>fish oil</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ω-3 полиненасыщенные жирные кислоты</kwd><kwd>ω-3 эритроцитарный индекс</kwd><kwd>когнитивные функции</kwd><kwd>устойчивость внимания</kwd><kwd>концентрация внимания</kwd><kwd>дети</kwd><kwd>рыбий жир</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Минченко Л.А. Омега-3-полиненасыщенные жирные кислоты: медико-биологическая ценность. 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