Teething syndrome in infants: competent correction of symptoms. A review
- Authors: Skakodub A.A.1, Kozlitina I.A.1, Filatova O.O.2, Ugai D.V.2
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Affiliations:
- Sechenov First Moscow State Medical University (Sechenov University)
- Saint Petersburg State Pediatric Medical University
- Issue: No 2 (2025)
- Pages: 143-149
- Section: Articles
- URL: https://pediatria.orscience.ru/2658-6630/article/view/687438
- DOI: https://doi.org/10.26442/26586630.2025.2.203349
- ID: 687438
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Abstract
Teething in children is a normal physiological process consisting of the intraosseous movement of a tooth in the jaw until it appears in the oral cavity. This process may be accompanied by local and systemic symptoms. Currently, local medicinal and non-medicinal treatments for teething syndrome are recommended. As part of an integrated approach, it is rational to use Cholisal® dental gel, which has the necessary levels of safety for infants and effectiveness when used according to the instructions.
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About the authors
Alla A. Skakodub
Sechenov First Moscow State Medical University (Sechenov University)
Author for correspondence.
Email: skalla71@mail.ru
D. Sci. (Med.)
Russian Federation, MoscowIuliia A. Kozlitina
Sechenov First Moscow State Medical University (Sechenov University)
Email: skalla71@mail.ru
ORCID iD: 0000-0002-4964-7441
Cand. Sci. (Med.)
Russian Federation, MoscowOlga O. Filatova
Saint Petersburg State Pediatric Medical University
Email: skalla71@mail.ru
ORCID iD: 0000-0002-1931-7361
Assistant
Russian Federation, Saint PetersburgDenis V. Ugai
Saint Petersburg State Pediatric Medical University
Email: skalla71@mail.ru
ORCID iD: 0009-0004-6480-6721
pediatrician
Russian Federation, Saint PetersburgReferences
- Кисельникова Л.П., Царев В.Н., Подпорин М.С., Балафендиева Ф.М. Клинико-микробиологическая эффективность лечения затрудненного прорезывания временных зубов. Педиатрия им. Г.Н. Сперанского. 2023;102(4):73-9 [Kiselnikova LP, Tsarev VN, Podporin MS, Balafendieva FM. Clinical and microbiological efficacy of the treatment of difficult temporary teeth eruption in children. Pediatria n.a. G.N. Speransky. 2023;102(4):73-9 (in Russian)]. doi: 10.24110/0031-403X-2023-102-4-73-79
- Ashley MP. It's only teething. A report of the myths and modern approaches to teething. Br Dent J. 2001;191(1):4-8. doi: 10.1038/sj.bdj.4801078
- Клинические рекомендации. Синдром прорезывания временных зубов. Стоматологическая ассоциация России. Режим доступа: https://e-stomatology.ru/director/protokols/clin_rec_jan2025/056.docx. Ссылка активна на 14.03.2025 [Clinical guidelines. Syndrome of eruption of primary teeth. Dental Association of Russia. Available at: https://e-stomatology.ru/director/protokols/clin_rec_jan2025/056.docx Accessed: 14.03.2025 (in Russian)].
- Memarpour M, Soltanimehr E, Eskandarian T. Signs and symptoms associated with primary tooth eruption: a clinical trial of nonpharmacological remedies. BMC Oral Health. 2015;15:88. doi: 10.1186/s12903-015-0070-2
- Massignan C, Cardoso M, Porporatti AL, et al. Signs and symptoms of primary tooth eruption: A meta-analysis. Pediatrics. 2016;137:e20153501.
- Балафендиева Ф.М., Кисельникова Л.П. Анализ некоторых факторов, влияющих на прорезывание временных зубов. Проблемы стоматологии. 2023;1:99-104 [Balafendieva FM, Kiselnikova LP. Analysis of some factors affecting the eruption of temporary teeth. The Actual Problems in Dentistry. 2023;1:99-104 (in Russian)]. doi: 10.18481/2077-7566-2023-19-1-99-104
- Macknin M, Piedmonte M, Jacobs J, Skibinski C. Symptoms associated with infant teething: a prospective study. Pediatrics. 2000;105:747-52.
- Kahn M, Lucchini M, Oster E, et al. Does Teething Disrupt Infant Sleep? A Longitudinal Auto-Videosomnography Study. J Pediatr. 2025;279:114461. doi: 10.1016/j.jpeds.2025.114461
- Markman L. Teething: facts and fiction. Pediatr Rev. 2009;30(8):e59-64. doi: 10.1542/pir.30-8-e59
- Зайцева О.В. Формирование иммунитета: Актуальные вопросы педиатрии. Аллергология и иммунология в педиатрии. 2014;2(37):12-22 [Zaytseva OV. Formirovanie immuniteta: Aktual'nyye voprosy pediatrii. Allergologiya i immunologiya v pediatrii. 2014;2(37):12-22 (in Russian)]. doi: 10.24411/2500-1175-2014-00013
- McIntyre GT, McIntyre GM. Teething troubles? Br Dent J. 2002;192(5):251-5. doi: 10.1038/sj.bdj.4801349
- Adimorah GN, Ubesie AC, Chinawa JM. Mothers' beliefs about infant teething in Enugu, South-East Nigeria: a cross sectional study. BMC Res Notes. 2011;4:228. doi: 10.1186/1756-0500-4-228
- Wake M, Hesketh K, Lucas J. Teething and tooth eruption in infants: A cohort study. Pediatrics. 2000;106:1374-9.
- Дроботько Л.Н., Зуева Т.Е., Кисельникова Л.П. Синдром прорезывания зубов: когда и как лечить. Фарматека. 2019;26(10):77-81 [Drobotko LN, Zuyeva TE, Kiselnikova LP. Sindrom prorezyvaniia zubov: kogda i kak lechit. Farmateka. 2019;26(10):77-81 (in Russian)]. doi: 10.18565/pharmateca.2019.10.77-81
- Заплатников А.Л., Касьянова А.Н., Майкова И.Д. Синдром прорезывания зубов у младенцев: новый взгляд на старую проблему. РМЖ. 2018;5(II):68-71 [Zaplatnikov AL, Kasyanova AN, Maikova ID. Teething syndrome in infants: a new look at the old problem. RMJ. 2018;5(II):68-71 (in Russian)].
- Шкаева И.Е., Солнцева С.А., Никулина О.С., и др. Токсичность и опасность фталатов (Анализ литературных сведений). Токсикологический вестник. 2019;6:3-9 [Shkaeva IE, Solntseva SA, Nikulina OS, et al. Toxicity and hazard of phthalates (Literature review). Toxicological Review. 2019;6:3-9 (in Russian)].
- Крихели Н.И., Пустовойт Е.В., Дарсигова З.Т. Эффективность применения препарата Холисал в комплексном лечении заболеваний слизистой оболочки полости рта и пародонта. Стоматология. 2022;101(6):98-102 [Krikheli NI, Pustovoit EV, Darsigova ZT. The effectiveness of the drug Cholisal in the complex treatment of oral mucosa and periodontal diseases. Stomatology. 2022;101(6): 98-102 (in Russian)].
- Vohra R, Huntington S, Koike J, et al. Pediatric Exposures to Topical Benzocaine Preparations Reported to a Statewide Poison Control System. West J Emerg Med. 2017;18(5):923-7. doi: 10.5811/westjem.2017.6.33665
- Teoh L, Moses GM. Are teething gels safe or even necessary for our children? A review of the safety, efficacy and use of topical lidocaine teething gels. J Paediatr Child Health. 2020;56(4):502-5. doi: 10.1111/jpc.14769
- American Academy of Pediatrics (AAPD). Fever and antipyretic use in children. Pediatrics. 2016;137(3).
- American Academy of Pediatric Dentistry (AAPD). Guideline on the management of teething. Pediatr Dentistry. 2020;42(4):269-74.
- Alberta Health Services. Teething care instructions. 2023. Available at: https://myhealth.alberta.ca/Health/aftercareinformation/pages/conditions.aspx?hwid=uh3717. Accessed: 14.03.2025.
- HSE Ireland. Advice on teething and dental care. 2022. Available at: https://www2.hse.ie/babies-children/parenting-advice/caring-for-a-new-baby/teething-gums/ Accessed: 14.03.2025.
- Mayo Clinic. Teething: signs and remedies. Available at: https://www.mayoclinic.org/healthy-lifestyle/infant-and-toddler-health/in-depth/teething/art-20046378 Accessed: 14.03.2025.
