Synthesis of Formylphenyl 1-Oxo-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole-7-carboxylates and Their (E)-1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-yliminomethyl Derivatives

Мұқаба

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

Formylphenyloxohydroepoxyisoindole carboxylates were prepared by the reaction of 4-hydroxy-3-methoxy-, 4-hydroxy-3-ethoxy- and 3-hydroxy-4-methoxybenzaldehydes with substituted isoindolecarboxylic acids {2-methyl-1-oxo-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole-7-carboxylic, 2-(3,4-dimethoxyphenethyl)1-oxo-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole-7-carboxylic, 2-(benzo[d][1,3]dioxol-5-ylmethyl)-1-oxo1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole-7-carboxylic, 6-oxo-3,4,6,6a,7,8-hexahydro-2H,10bH-8,10a-epoxy[1,3]oxazino[2,3-a]isoindole-7-carboxylic, 2-(2,3-dichlorobenzyl)-1-oxo-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole-7-carboxylic} in dichloromethane in the presence of dicyclohexylcarbodiimide. The corresponding (E)-azomethines were synthesized by condensation of formylphenyloxohydroepoxyisoindole carboxylates with 4-amino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one in methanol.

Авторлар туралы

E. Dikusar

Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus

Хат алмасуға жауапты Автор.
Email: evgen_58@mail.ru
ORCID iD: 0000-0002-3868-1871
Белоруссия, Minsk, 220072

E. Akishina

Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus

Email: evgen_58@mail.ru
ORCID iD: 0000-0002-0803-8623
Белоруссия, Minsk, 220072

N. Zhukovskaya

Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus

Email: evgen_58@mail.ru
ORCID iD: 0000-0003-2795-4261
Ресей, Minsk, 220072

I. Kolesnik

Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus

Email: evgen_58@mail.ru
ORCID iD: 0000-0003-4921-4299
Белоруссия, Minsk, 220072

E. Margun

Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus

Email: evgen_58@mail.ru
ORCID iD: 0009-0002-4843-3916
Белоруссия, Minsk, 220072

S. Kovalskaya

Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus

Email: evgen_58@mail.ru
ORCID iD: 0009-0002-3445-2809
Белоруссия, Minsk, 220072

K. Alekseeva

RUDN University

Email: evgen_58@mail.ru
ORCID iD: 0000-0001-6414-7122
Ресей, Moscow, 117198

N. Logvinenko

RUDN University

Email: evgen_58@mail.ru
ORCID iD: 0000-0001-8564-7353
Ресей, Moscow, 117198

D. Menshikova

RUDN University

Email: evgen_58@mail.ru
ORCID iD: 0000-0001-8642-1209
Ресей, Moscow, 117198

M. Grigoriev

Frumkin Institute of Physical Chemistry and Electrochemistry of the Russian Academy of Sciences

Email: evgen_58@mail.ru
ORCID iD: 0000-0002-6363-5535
Ресей, Moscow, 119071

V. Potkin

Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus

Email: evgen_58@mail.ru
ORCID iD: 0000-0003-0250-837X
Белоруссия, Minsk, 220072

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