Resolution of the Council of Experts “Dysbiosis. Immediate and long-term consequences of microbiome disorders and options for their correction with probiotics”
- Authors: Gorelov A.V.1,2, Zakharova I.N.3, Khavkin A.I.4, Kafarskaya L.I.5, Usenko D.V.2, Belmer S.V.5, Kornienko E.A.6, Privorotsky V.F.6, Krasnov V.V.7, Kondyurina E.G.8, Panfilova V.N.9, Tkhakushinova N.K.10, Plaksina A.N.11, Rychkova O.A.12, Pechkurov D.V.13, Nizhevich A.A.14, Fayzullina R.A.15, Yablokova E.A.1,4
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Affiliations:
- Sechenov First Moscow State Medical University (Sechenov University)
- Central Research Institute of Epidemiology
- Russian Medical Academy of Continuous Professional Education
- Research Clinical Institute of Childhood
- Pirogov Russian National Research Medical University
- Saint Petersburg State Pediatric Medical University
- Privolzhsky Research Medical University
- Novosibirsk State Medical University
- Voyno-Yasenetsky Krasnoyarsk State Medical University
- Kuban State Medical University
- Ural State Medical University
- Tyumen State Medical University
- Samara State Medical University
- Bashkir State Medical University
- Kazan State Medical University
- Issue: No 1 (2022)
- Pages: 90-96
- Section: Articles
- URL: https://pediatria.orscience.ru/2658-6630/article/view/107234
- DOI: https://doi.org/10.26442/26586630.2022.1.201535
- ID: 107234
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Abstract
The appearance of new high-tech microbiological research methods has significantly changed the understanding of the human microbiome. The purpose of the meeting of the Council of Experts “Dysbiosis. The immediate and long-term consequences of microbiome disorders and options for their correction with probiotics” was the definition of modern positions about possible methods of studying the intestinal microbiome, the possibilities of correcting dysbiosis, the use of Saccharomyces boulardii CNCM I-745 to correct microbiome disorders in various clinical situations. The criteria of the microbiological “norm” for the intestinal microbiome have not been definitively established. To study the microbiome, a set of methods is used that combine cultural and molecular genetic methods that complement each other. Currently, there are no clinical markers of dysbiosis, and laboratory markers of dysbiosis require modification.
Probiotics can provide restoration of the intestinal microbiota. The effectiveness and safety of the use of Saccharomyces boulardii CNCM I-745 for this purpose has been proven. In the case of acute intestinal infection, antibiotic-associated diarrhea, and the consequences of HP infection eradication, studies have a high level of evidence.
This article is a reprint. Primary Publication: Gorelov AV, Zakharova IN, Khavkin AI, Kafarskaya LI, Usenko DV, Belmer SV, Kornienko EA, Privorotsky VF, Krasnov VV, Kondyurina EG, Panfilova VN, Tkhakushinova NKh, Plaksina AN, Rychkova OA, Pechkurov DV, Nizhevich AA, Fayzullina RA, Yablokova EA. Resolution of the Council of Experts “Dysbiosis. Immediate and long-term consequences of microbiome disorders and options for their correction with probiotics”. Vopr. prakt. pediatr. (Clinical Practice in Pediatrics). 2022;17(1):213–221 (in Russian). DOI: 10.20953/1817-7646-2022-1-213-221. With the permission of the copyright holder. Published with reductions.
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About the authors
Aleksandr V. Gorelov
Sechenov First Moscow State Medical University (Sechenov University); Central Research Institute of Epidemiology
Author for correspondence.
Email: agorelov_05@mail.ru
D. Sci. (Med.), Prof., Acad. RAS
Russian Federation, Moscow; MoscowIrina N. Zakharova
Russian Medical Academy of Continuous Professional Education
Email: agorelov_05@mail.ru
D. Sci. (Med.), Prof.
Russian Federation, MoscowAnatolii I. Khavkin
Research Clinical Institute of Childhood
Email: agorelov_05@mail.ru
D. Sci. (Med.), Prof.
Russian Federation, MoscowLiudmila I. Kafarskaya
Pirogov Russian National Research Medical University
Email: agorelov_05@mail.ru
D. Sci. (Med.), Prof.
Russian Federation, MoscowDenis V. Usenko
Central Research Institute of Epidemiology
Email: agorelov_05@mail.ru
D. Sci. (Med.)
Russian Federation, MoscowSergei V. Belmer
Pirogov Russian National Research Medical University
Email: agorelov_05@mail.ru
D. Sci. (Med.), Prof., Acad. RANS
Russian Federation, MoscowElena A. Kornienko
Saint Petersburg State Pediatric Medical University
Email: agorelov_05@mail.ru
D. Sci. (Med.), Prof.
Russian Federation, Saint PetersburgValerii F. Privorotsky
Saint Petersburg State Pediatric Medical University
Email: agorelov_05@mail.ru
D. Sci. (Med.), Prof.
Russian Federation, Saint PetersburgViktor V. Krasnov
Privolzhsky Research Medical University
Email: agorelov_05@mail.ru
D. Sci. (Med.), Prof.
Russian Federation, Nizhny NovgorodElena G. Kondyurina
Novosibirsk State Medical University
Email: agorelov_05@mail.ru
D. Sci. (Med.), Prof.
Russian Federation, NovosibirskViktoriia N. Panfilova
Voyno-Yasenetsky Krasnoyarsk State Medical University
Email: agorelov_05@mail.ru
D. Sci. (Med.)
Russian Federation, KrasnoyarskNafiset Kh. Tkhakushinova
Kuban State Medical University
Email: agorelov_05@mail.ru
D. Sci. (Med.), Assoc. Prof.
Russian Federation, KrasnodarAnna N. Plaksina
Ural State Medical University
Email: agorelov_05@mail.ru
Cand. Sci. (Med.)
Russian Federation, YekaterinburgOlga A. Rychkova
Tyumen State Medical University
Email: agorelov_05@mail.ru
D. Sci. (Med.)
Russian Federation, TyumenDmitrii V. Pechkurov
Samara State Medical University
Email: agorelov_05@mail.ru
D. Sci. (Med.), Prof.
Russian Federation, SamaraAleksandr A. Nizhevich
Bashkir State Medical University
Email: agorelov_05@mail.ru
D. Sci. (Med.), Prof.
Russian Federation, UfaRezeda A. Fayzullina
Kazan State Medical University
Email: agorelov_05@mail.ru
D. Sci. (Med.), Prof.
Russian Federation, KazanEkaterina A. Yablokova
Sechenov First Moscow State Medical University (Sechenov University); Research Clinical Institute of Childhood
Email: agorelov_05@mail.ru
Cand. Sci. (Med.)
Russian Federation, Moscow; MoscowReferences
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