THE VALUE OF INSTRUMENTAL METHODS IN THE DIAGNOSTICS OF PNEUMONIA IN CORONAVIRUS INFECTION


Cite item

Full Text

Abstract

Main goal in the managing of the coronavirus infections is the timely diagnosis of the viral pneumonia. Along with the key clinical signs main instrumental methods are computed tomography (CT) and lungs X-ray. However, in the lungs tissues evaluation in viral pneumonias, including ones associated with a COVID-19, X-ray are not very informative. We propose the tactic of the early instrumental diagnostic of lung's degree of lesion and functional state in coronavirus infection. As the lung CT is more informative in the evaluation of the state of the lungs, it has to be done in the first place. In case of general lack of resources and high demand for CT, lung ultrasound may be performed as a secondary measure. Limitations and low specificity of lung ultrasound should be considered in evaluation of its results. If some need arise to evaluate the functional state of the lungs, we propose the spirometry. Bilateral interstitial pneumonia would be suspected if restrictive pattern is registered. In that case diffusion capacity and total lung capacity are evaluated as well.

Full Text

Restricted Access

About the authors

Vladislav B. Voitenkov

Pediatric Research and Clinical Center for Infectious Diseases

Email: vlad203@inbox.ru
Saint Petersburg, Russia

Natalya V. Marchenko

Pediatric Research and Clinical Center for Infectious Diseases

Saint Petersburg, Russia

Natalya V. Skripchenko

Pediatric Research and Clinical Center for Infectious Diseases

Saint Petersburg, Russia

Marina G. Kapiton

Pediatric Research and Clinical Center for Infectious Diseases

Saint Petersburg, Russia

Mariia A. Bedova

Pediatric Research and Clinical Center for Infectious Diseases

Saint Petersburg, Russia

References

  1. Ruuskanen O, Lahti E, Jennings LC et al. Viral pneumonia. Lancet 2011; 377 (9773): 1264-75. doi: 10.1016/S0140-6736(10)61459-6
  2. Galvan JM, Rajas O, Aspa J. Review of Non-Bacterial Infections in Respiratory Medicine: Viral Pneumonia. Arch Bronconeumol 2015; 51 (11): 590-7. doi: 10.1016/j.arbres.2015.02.015
  3. Горенчук А.Н., Куликов П.В., Жоголев С.Д. и др. Этиологическая характеристика острых болезней органов дыхания у военнослужащих западного военного округа в 2014-2019 гг Вестн. Рос. военно-медицинской академии. 2020; 1 (69): 81-6. [Gorenchuk A.N., Kulikov PV., Zhogolev S.D. et al. Etiologicheskaia kharakteristika ostrykh boleznei organov dykhaniia u voennosluzhashchikh zapadnogo voennogo okruga v 2014-2019 gg. Vestn. Ros. voenno-meditsinskoi akademii. 2020; 1 (69): 81-6 (in Russian).]
  4. Sorensen MD, Sorensen B, Gonzalez-Dosal R et al. Severe acute respiratory syndrome (SARS): development of diagnostics and antivirals. Ann New York Acad Sci 2006; 1067 (1): 500. doi: 10.1196/annals.1354.072
  5. Distribution of confirmed cases of MERS-CoV by place of infection and month of onset, from March 2012 to 2 December 2019. Available at: https://www.ecdc.europa.eu/en/publications-data/distribution-confirmed-cases-mers-cov-place-infection-and-month-onset-march-2012
  6. Novel Coronavirus (2019-nCoV). Situation Report - 8. World Health Organization. https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200128-sitrep-8-ncov-cleared.pdf?sfvrsn=8b671ce5_2
  7. Yu F, Du L, Ojcius DM et al. Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China. Microbes Infect 2020; 22 (2): 74-9. doi: 10.1016/j.micinf.2020.01.003
  8. Song Z, Xu Y, Bao L et al. From SARS to MERS, Thrusting Coronaviruses into the Spotlight. Viruses 2019; 11 (1): 59. doi: 10.3390/v11010059
  9. Lu R, Zhao X, Li J et al. Genomic characterization and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 2020; 395 (10224): 565-74. doi: 10.1016/S0140-6736 (20)30251-8
  10. Wan Y, Shang J, Graham R et al. Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS. J Virol 2020; 94 (7): e00127-20.
  11. Yuan Y, Cao D, Zhang Y et al. Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains. Nat Commun 2017; 8: 15092.
  12. Hulswit RJ, de Haan CA, Bosch BJ. Coronavirus Spike Protein and Tropism Changes. Adv Virus Res 2016; 96: 29-57.
  13. Khan S, Ali A, Siddique R, Nabi G. Novel coronavirus is putting the whole world on alert. J Hosp Infect 2020; 104 (3): 252-3.
  14. Huang C, Wang Y, Li X, Ren L. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395: 497-506.
  15. Chen N, Zhou M, Dong X, Qu J. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020; 395 (10223): 507-13.
  16. Никифоров В.В., Суранова ТГ., Миронов А.Ю., Забозлаев Ф.Г. Новая коронавирусная инфекция (COVID-19): этиология, эпидемиология, клиника, диагностика, лечение и профилактика. Учебно-методическое пособие. М.: Академия постдипломного образования ФГБУ «ФНКЦ ФМБА России», 2020.
  17. Huang C, Wang Y, Li X, Ren L. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395: 497-506.
  18. Chen N, Zhou M, Dong X, Qu J. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020; 395 (10223): 507-13.
  19. Li YC, Bai WZ, Hashikawa T. The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients. J Med Virol 2020; doi: 10.1002/jmv.25728
  20. ARTP COVID19 Update - 18th March 2020.
  21. Чучалин А.Г, Айсанов З.Р, Чикина С.Ю. и др. Федеральные клинические рекомендации Российского респираторного общества по использованию метода спирометрии. Пульмонология. 2014; 6: 11-24. doi: 10.18093/0869-0189-2014-0-6-11-24 @@Chuchalin A.G., Aisanov Z.R., Chikina S.Iu. et al. Federal'nye klinicheskie rekomendatsii Rossiyskogo respiratornogo obshchestva po ispol'zovaniiu metoda spirometrii. Pul'monologiia. 2014; 6: 11-24. doi: 10.18093/0869-0189-2014-0-6-11-24 (in Russian).
  22. Miller MR, Hankinson J, Brusasco V et al. Standardization of spirometry. Eur Respir J 2005; 26: 319-38.
  23. Новая коронавирусная инфекция (COVID-19): этиология, эпидемиология, клиника, диагностика, лечение и профилактика. Учебно-методическое пособие №21. М., 2020. @@New coronavirus infection (COVID-19): etiology, epidemiology, clinic, diagnosis, treatment and prevention. Teaching aid №21. Moscow, 2020 (in Russian).
  24. Ai T, Yang Z, Hou H et al. Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology 2020; p. 200642. doi: 10.1148/radiol.2020200642
  25. Knipe H, Bell DJ et al. COVID-19. https: //radiopaedia.org/articles/covid-19-3
  26. Handbook of COVID-19 Prevention and Treatment. Ed. by T.Liang. Zhejiang University School of Medicine, 2020.
  27. Морозов С.П., Проценко Д.Н., Сметанина С.В. и др. Лучевая диагностика короновирусной болезни (COVID-19): организация, методология, интерпретация результатов. Сер.: Лучшие практики лучевой и инструментальной диагностики. Вып. 65. М.: ГБУЗ НПКЦ ДиТ ДЗМ, 2020.
  28. Buonsenso D, Piano A, Raffaelli F et al. Point-of-Care Lung Ultrasound findings in novel coronavirus disease-19 pnemoniae: a case report and potential applications during COVID-19 outbreak. Eur Rev Med Pharmacol Sci 2020; 24 (5): 2776-80. doi: 10.26355/eurrev_202003_20549
  29. Soldati G, Smargiassi A, Inchingolo R et al. Is there a role for lung ultrasound during the COVID-19 pandemic? J Ultrasound Med 2020. doi: 10.1002/jum.15284
  30. Lung Ultra Sound and COVID-19 Pandemic. http: //sonomir.wordpress.com/
  31. Власенко А.В. Острый респираторный дистресс-синдром - что нового в 2020 году? https://mosgorzdrav.ru/uploads/imperavi/ru-RU/present_30032020_vlasenko.pdf @@Vlasenko A.V. Acute Respiratory Distress Syndrome - What's New in 2020? https: //mosgorzdrav.ru/uploads/imperavi/ru-RU/present_30032020_vlasenko.pdf (in Russian).

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2020 Consilium Medicum

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 74329 от 19.11.2018 г.