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For opinion, experts Association Pediatric Allergist and Immunologist of Russia a new definition of atopic eczema: chronic recurrent inflammation of the skin, arising as a result of a violation of the epidermal barrier and entailing its further dysfunction. Maximum development atopic dermatitis reaches on the background of predisposition to IgE-mediated hypersensitivity, implemented in sensitization to surrounding allergens. Key points: 1. Allergic sensitization is not the only and main cause of atopic dermatitis. 2. Allergy special examination should be carried out to prove atopic dermatitis with food allergy. 3. Conducting eliminationprovocation tests with food allergens is necessary in case of doubt about the of allergy food reactions. 4. We recommend using skin prick test and specific IgE (solid-phase ELISA) providing a high sensitivity of 0.1-100 mgA/L. 5. A proven allergic reaction to food requires the exclusion of all foods that contain this protein for a time enough for the development of tolerance. 6. The expectation of cross-reactions should not be the reason for the exclusion of food. Only an elimination and provocation diet (test) is able to prove food intolerances. 7. Elimination diet-a temporary action, because after a few months of complete exclusion of the allergenic product from the diet, most children will be able to eat previously intolerant food. 8. In infants, the best nutrition option is breastfeeding for duration of 6 months. It is not advisable to delay the introduction of complementary foods and restriction of highly allergenic products if they are not proven hypersensitivity to it.

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About the authors

Yury S. Smolkin

Association Pediatric Allergist and Immunologist of Russia; Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies


Sergei S. Masalskiy

Association Pediatric Allergist and Immunologist of Russia; Scientific Clinical Consultative Center for Allergology and Immunology; Scientific Clinical Consultative Center for Allergology and Immunology

Andrei A. Cheburkin

Association Pediatric Allergist and Immunologist of Russia; Russian Medical Academy of Continious Proffessional Education

Igor A. Gorlanov

Saint Petersburg State Pediatric Continuous University


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