Influence of vitamin D on the immune response of the organism


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Abstract

A literature review is devoted to the effect of vitamin D on the body's immune response. Studies show that vitamin D is able to inhibit the synthesis of pro-inflammatory cytokines, and, as a result, play an important role in the formation of immune tolerance, which is important in infectious, autoimmune diseases and in patients after organ transplantation. Vitamin D can be used both as a prophylaxis and for therapeutic purposes for infectious diseases, in oncohematology, allergology, gastroenterology, and can also affect the intrauterine development of the fetus and the immune response of the newborn, reducing the risk of pregnancy pathology, risks of premature birth and placenta pathology, as well as reducing the frequency, severity and risk of adverse outcome in newborns with congenital and acquired infectious diseases. In the postnatal period, normal provision with vitamin D not only reduces the frequency, but also prevents the formation of severe forms of autoimmune, allergic diseases in children and adolescents.

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Irina N. Zakharova

Russian Medical Academy of Continuous Professional Education

Email: zakharova-rmapo@yandex.ru

Stanislav V. Maltsev

Russian Medical Academy of Continuous Professional Education

Andrei L. Zaplatnikov

Russian Medical Academy of Continuous Professional Education

Leonid Ya. Klimov

Stavropol State Medical University

Aleksandr N. Pampura

Pirogov Russian National Research Medical University

Viktoriia A. Kuryaninova

Stavropol State Medical University

Irina V. Berezhnaya

Russian Medical Academy of Continuous Professional Education

Ekaterina D. Zhdakaeva

Russian Medical Academy of Continuous Professional Education

Mariia A. Simakova

Russian Medical Academy of Continuous Professional Education

Anna N. Tsutsaeva

Stavropol State Medical University

Svetlana V. Dolbnya

Stavropol State Medical University

Natalia E. Verisokina

Stavropol State Medical University

Anatolii A. Krushelnitsky

Shchyolkovo Perinatal Center

Anastasiia V. Makhaeva

Children's City Clinic №140

Dmitrii A. Sychev

Russian Medical Academy of Continuous Professional Education

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