VIOLATIONS OF THE VENTILATION FUNCTION OF THE LUNGS IN CHILDREN WITH SEVERE NEUROGENIC AND DYSPLASTIC DEFORMITIES OF THE SPINE


Cite item

Full Text

Abstract

Aim. Comparative evaluation of ERF in children with dysplastic and neurogenic spinal deformities and the determination of their correlation with the radiological parameters of the severity and mobility of the deformation. Materials and methods. A comparative clinical and radiological study was carried out to determine the parameters of the external respiration function (ERF) in children with severe dysplastic (61 patients), neurogenic spinal deformities (30 patients) and conditionally healthy children without spinal deformities (reference group - 30 children) over the age of 6 under 17 years old. Patients were hospitalized in the neuro-orthopedic department of the Research Institute of Pediatric Surgery FSAI "Scientific Research Center for Children's Health" from 2010 to 2020 to further examine and perform surgical correction of spinal deformity. Results. Significantly more severe disturbances of the ERF were revealed in children with neurogenic spinal deformities, which were accompanied by a decrease in conductivity along the bronchi of all calibers: large, medium and small, as evidenced by the indicators MOS25(%D), MOS50(%D) and MOS75(%D), while dysplastic deformities of the spine were characterized mainly by impaired conduction in the small bronchi - MOS75(%D). Conclusions. A high correlation was established between the radiological indicators of the severity and mobility of spinal deformity with revealed impairments of the ERF, to a greater extent in patients with neurogenic scoliosis, which allows us to judge the severity of the course of scoliotic disease and make a timely decision on the need for surgical correction.

Full Text

Restricted Access

About the authors

Oleg B. Chelpachenko

National Medical Research Center for Children's Health

Email: chelpachenko81@mail.ru
Moscow, Russia

Andrei P. Fisenko

National Medical Research Center for Children's Health

Moscow, Russia

Konstantin V. Zherdev

National Medical Research Center for Children's Health

Moscow, Russia

Sergei P. Yatsyk

National Medical Research Center for Children's Health

Moscow, Russia

Olga I. Simonova

National Medical Research Center for Children's Health

Moscow, Russia

References

  1. Зайдман А.М. и др. Сколиотическая болезнь: 50-летний опыт исследований. Сиб. науч. мед. журн. 2017; 37 (6): 76-85. @@Zaidman A.M. et al. Skolioticheskaia bolezn': 50-letnii opyt issledovanii. Sib. nauch. med. zhurn. 2017; 37 (6): 76-85 (in Russian).
  2. Еналдиева Р.В., Автандилов А.Г., Ветрилэ С.Т и др. Изменения гемодинамики малого и большого кругов кровообращения при сколиотической болезни. Хирургия позвоночника. 2006; 1: 44-9. @@Enaldieva R.V., Avtandilov A.G., Vetrile S.T et al. Izmeneniia gemodinamiki malogo i bol'shogo krugov krovoobrashcheniia pri skolioticheskoi bolezni. Khirurgiia pozvonochnika. 2006; 1: 44-9 (in Russian).
  3. Alexandre AS, Sperandio EF, Yi LC et al. Photogrammetry: a proposal of objective assessment of chest wall in adolescent idiopathic scoliosis. Rev Paul Pediatr 2019; 37 (2): 225-33. doi: 10.1590/1984-0462/;2019;37;2;00001
  4. Сошникова Е.В., Ильясевич ИА., Тесаков Д.К. Особенности патологического изменения функции внешнего дыхания у пациентов с хирургическими деформациями позвоночника при сколиозе. Ульяновский медико-биологический журн. 2016; 4: 65-6.
  5. Полиорганные нарушения при дисплазиях соединительной ткани у детей. Алгоритмы диагностики. Тактика ведения. Проект российских рекомендаций. Часть 2. Мед. вестн. Северного Кавказа. 2016; 11 (2). Вып. 2; с. 239-63.
  6. Еналдиева Р.В. Клинико-функциональная оценка и обоснование коррекции нарушений кардиогемодинамики при сколиотической болезни. Автореф. дис.. д-ра мед. наук. М., 2006. @@Enaldieva R.V. Kliniko-funktsional'naia otsenka i obosnovanie korrektsii narushenii kardiogemodinamiki pri skolioticheskoi bolezni. Avtoref. dis.. d-ra med. nauk. Moscow, 2006 (in Russian).
  7. Михайловский М.В., Фомичев Н.Г. Хирургия деформаций позвоночника. Новосибирск, 2011. @@Mikhailovsky M.V., Fomichev N.G. Spinal deformity surgery. Novosibirsk, 2011 (in Russian).
  8. Am ric i E, Suciu O, Onofrei RR et al. Respiratory function, functional capacity, and physical activity behaviours in children and adolescents with scoliosis. J Int Med Res 2019. doi: 10.1177/0300060519895093
  9. Dobbs MB, Goldstein jA. Neuromuscular Scoliosis. Medscape 2019.
  10. Vialle R, Thevenin-Lemoine C, Mary P Neuromuscular scoliosis. Orthop Traumatol Surg Res 2013; 99 (1 Suppl.): S124-39. doi: 10.1016/j.otsr.2012.11.002
  11. Fleck D, Curry C, Donnan K et al. Investigating the clinical use of structured light plethysmography to assess lung function in children with neuromuscular disorders. PLoS One 2019; 14 (8): e0221207. doi: 10.1371/journal.pone.0221207
  12. Funk S, Lovejoy S, Mencio G, Martus J. Rigid Instrumentation for Neuromuscular Scoliosis Improves Deformity Correction Without Increasing Complications. Spine 2016; 41 (1): 46-52.
  13. Cheuk DK, Wong V, Wraige E et al. Surgery for scoliosis in Duchenne muscular dystrophy. Cochrane Database of Systematic Reviews 2015.
  14. Farber HJ, Phillips WA, Kocab KL et al. Impact of scoliosis surgery on pulmonary function in patients with muscular dystrophies and spinal muscular atrophy. Pediatr Pulmonol 2020. doi: 10.1002/ppul.24664
  15. Кулешов А.А. Тяжелые формы сколиоза. Оперативное лечение и функциональные особенности некоторых органов и систем. Дис.. д-ра мед. наук. М., 2007. @@Kuleshov A.A. Tiazhelye formy skolioza. Operativnoe lechenie i funktsional'nye osobennosti nekotorykh organov i sistem. Dis. d-ra med. nauk. Moscow, 2007 (in Russian).
  16. Ветрилэ С.Т., Кулешов АА., Кисель А.А. и др. Дорсальная хирургическая коррекция сколиоза инструментарием Cotrel Dubousset с предварительной галопельвиктракцией и без нее. Хирургия позвоночника. 2005; 4: 32-9. @@Vetrile S.T., Kuleshov A.A., Kisel' A.A. et al. Dorsal'naia khirurgicheskaia korrektsiia skolioza instrumentariem Cotrel Dubousset s predvaritel'noi galopel'viktraktsiei i bez nee. Khirurgiia pozvonochnika. 2005; 4: 32-9 (in Russian).
  17. Ветрилэ С.Т., Кулешов АА, Ветрилэ М.С., Челпаченко О.Б. Оперативное лечение тяжелых протяженных кифотических деформаций грудного и поясничного отделов позвоночника. Хирургия позвоночника. 2009; 3: 20-9. @@Vetrile S.T., Kuleshov A.A., Vetrile M.S., Chelpachenko O.B. Operativnoe lechenie tiazhelykh protiazhennykh kifoticheskikh deformatsii grudnogo i poiasnichnogo ot-delov pozvonochnika. Khirurgiia pozvonochnika. 2009; 3: 20-9 (in Russian).

Copyright (c) 2020 Consilium Medicum

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 74329 от 19.11.2018 г.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies