Active specific immunoprophylaxis of influenza in the context of the COVID-19 pandemic and the beginning of vaccination against coronavirus infection caused by the SARS-CoV-2 virus

Cover Page

Abstract


A literature review based on the analysis of data published in the open press or available in electronic form on the official websites of international and national professional medical communities, as well as government regulatory bodies, is devoted to the issues of influenza immunization in the context of the COVID-19 pandemic and the start of vaccination against coronavirus infection caused by the SARS-CoV-2 virus. It is emphasized that influenza vaccinations significantly reduce the incidence and frequency of severe forms of influenza infection, which is accompanied by a decrease in the burden on the healthcare system and the preservation of reserves to combat the COVID-19 pandemic. Preliminary data are presented on the positive impact of influenza immunization on the incidence, severity and outcome of COVID-19, especially in people over the age of 65. Changes were noted in the National Immunization Schedule aimed at increasing coverage with influenza vaccinations, as well as at the start of vaccination against coronavirus infection caused by the SARS-CoV-2 virus, with the allocation of priority populations for priority immunization.


Full Text

Restricted Access

About the authors

Andrei L. Zaplatnikov

Russian Medical Academy of Continuous Professional Education

Author for correspondence.
Email: zaplatnikov@mail.ru
ORCID iD: 0000-0003-1303-8318

Russian Federation, Moscow

D. Sci. (Med.), Prof.

Elena I. Burtseva

Gamaleya National Research Center of Epidemiology and Microbiology

Email: elena-burtseva@yandex.ru
ORCID iD: 0000-0003-2518-6801

Russian Federation, Moscow

D. Sci. (Med.)

Asiia A. Girina

Khanty-Mansiysk State Medical Academy

Email: doctor_okb@mail.ru
ORCID iD: 0000-0002-5281-1564

Russian Federation, Khanty-Mansiysk

Cand. Sci. (Med.)

Viktoriia I. Svintsitskaia

Russian Medical Academy of Continuous Professional Education

Email: vishul@rambler.ru
ORCID iD: 0000-0002-9272-2339

Russian Federation, Moscow

Cand. Sci. (Med.)

Inga V. Lepiseva

Children’s Republican Hospital

Email: drb@zdrav10.ru

Russian Federation, Petrozavodsk

Chief doctor

References

  1. Coronavirus disease (COVID-19) pandemic. WHO, 20 December 2021. https://www.who.int/emergencies/diseases/novel-coronavirus-2019
  2. Информационный бюллетень о ситуации и принимаемых мерах по недопущению распространения заболеваний, вызванных новым коронавирусом. Роспотребнадзор Российской Федерации, 20.12.2020. https://www.rospotrebnadzor.ru/about/info/news/news_details.php?ELEMENT_ID=16327 [Informatsionnyi biulleten’ o situatsii i prinimaemykh merakh po nedopushcheniiu rasprostraneniia zabolevanii, vyzvannykh novym koronavirusom. Rospotrebnadzor Rossiiskoi Federatsii, 20.12.2020. https://www.rospotrebnadzor.ru/about/info/news/news_details.php?ELEMENT_ID=16327 (in Russian).]
  3. Coronavirus Disease (COVID-19) Dashboard. WHO, 20 December 2020. https://covid19.who.int/
  4. О подтвержденных случаях новой коронавирусной инфекции COVID-2019 в России. Роспотребнадзор, 20.12.2020. https://www.rospotrebnadzor.ru/about/ info/news/news_details.php?ELEMENT_ID=16328 [O podtverzhdennykh sluchaiakh novoi koronavirusnoi infektsii COVID-2019 v Rossii. Rospotrebnadzor, 20.12.2020. https://www.rospotrebnadzor.ru/about/ info/news/news_details.php?ELEMENT_ID=16328 (in Russian).]
  5. Информация о новой коронавирусной инфекции COVID-2019. Карта распространения в России. Министерство здравоохранения Российской Федерации, 20.12.2020. https://covid19.rosminzdrav.ru/ [Informatsiia o novoi koronavirusnoi infektsii COVID-2019. Karta rasprostraneniia v Rossii. Ministerstvo zdravookhraneniia Rossiiskoi Federatsii, 20.12.2020. https://covid19.rosminzdrav.ru/ (in Russian).]
  6. Commitment and call to action: Global collaboration to accelerate new COVID-19 health technologies. World Health Organization (WHO), 24 April 2020. https://www.who.int/news-room/detail/24-04-2020-commitment-and-call-to-action-global-collaboration-to-accelerate-new-covid-19-health-technologies
  7. WHO Draft Landscape of COVID-19 Candidate Vaccines. WHO, 17 December 2020. https://www.who.int/publications/m/item/draft-landscape-of-covid-19-candidate-vaccines
  8. Гам-КОВИД-Вак. Комбинированная векторная вакцина для профилактики коронавирусной инфекции, вызываемой вирусом SARS-CoV-2. Государственный реестр лекарственных средств, Москва, 11.08.2020. https://grls.rosminzdrav.ru/grls.aspx?s=гам-КОВИД-вак&m=tn [Gam-KOVID-Vak. Kombinirovannaia vektornaia vaktsina dlia profilaktiki koronavirusnoi infektsii, vyzyvaemoi virusom SARS-CoV-2. Gosudarstvennyi reestr lekarstvennykh sredstv, Moskva, 11.08.2020. https://grls.rosminzdrav.ru/grls.aspx?s=gam-KOVID-vak&m=tn (in Russian).]
  9. ЭпиВакКорона. Вакцина на основе пептидных антигенов для профилактики COVID-19. Государственный реестр лекарственных средств, Москва, 13.10.2020. https://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGuid=d8f07c35-7edc-49ab-8647-6b6865449167&t= [EpiVakKorona. Vaktsina na osnove peptidnykh antigenov dlia profilaktiki COVID-19. Gosudarstvennyi reestr lekarstvennykh sredstv, Moskva, 13.10.2020. https://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGuid=d8f07c35-7edc-49ab-8647-6b6865449167&t= (in Russian).]
  10. О внесении изменений в календарь профилактических прививок по эпидемическим показаниям, утвержденный приказом Министерства здравоохранения Российской Федерации от 21.03.2014 № 125н «Об утверждении национального календаря профилактических прививок и календаря профилактических прививок по эпидемическим показаниям». Приказ Министерства здравоохранения Российской Федерации от 09.12.2020 №1307н. http://publication.pravo.gov.ru/Document/View/0001202012160048 [O vnesenii izmenenii v kalendar’ profilakticheskikh privivok po epidemicheskim pokazaniiam, utverzhdennyi prikazom Ministerstva zdravookhraneniia Rossiiskoi Federatsii ot 21.03.2014 № 125n “Ob utverzhdenii natsional’nogo kalendaria profilakticheskikh privivok i kalendaria profilakticheskikh privivok po epidemicheskim pokazaniiam”. Prikaz Ministerstva zdravookhraneniia Rossiiskoi Federatsii ot 09.12.2020 no.1307n. http://publication.pravo.gov.ru/Document/View/0001202012160048 (in Russian).]
  11. Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices – United States, 2020–21 Influenza Season Recommendations and Reports. MMWR 2020; 69 (8): 1–24. https://www.cdc.gov/mmwr/volumes/69/rr/rr6908a1.htm?s_cid=rr6908a1_w
  12. Interim Guidance for Routine and Influenza Immunization Services During the COVID-19 Pandemic. CDC. Last reviewed: October 20, 2020. https://www.cdc.gov/vaccines/pandemic-guidance/index.html
  13. Gostin LO, Salmon DA. The Dual Epidemics of COVID-19 and Influenza: Vaccine Acceptance, Coverage, and Mandates. JAMA 2020; 324 (4): 335–6. doi: 10.1001/jama.2020.10802
  14. Singer ВD. COVID-19 and the next influenza season. Science Advances 2020; 6 (31): eabd0086. doi: 10.1126/sciadv.abd0086
  15. Paget J, Caini S, Cowling B et al. The impact of influenza vaccination on the COVID-19 pandemic? Evidence and lessons for public health policies. Vaccine 2020; 38 (42): 6485–6. doi: 10.1016/j.vaccine.2020.08.024
  16. Maltezo HC, Theodoridou К, Poland G. Influenza immunization and COVID-19. Vaccine 2020; 38: 6078–9. doi: 10.1016/j.vaccine.2020.07.058
  17. Grech V, Borg M. Influenza vaccination in the COVID-19 era. Early Human Development 2020; 148: 105116. doi: 10.1016/j.earlhumdev.2020.105116
  18. О мероприятиях по профилактике гриппа и острых респираторных вирусных инфекций, в том числе новой коронавирусной инфекции в эпидемическом сезоне 2020–2021 гг. Постановление Главного государственного санитарного врача Российской Федерации от 13.07.2020 №20. https://www.rospotrebnadzor.ru/documents/details.php?ELEMENT_ID=15051 [O meropriiatiiakh po profilaktike grippa i ostrykh respiratornykh virusnykh infektsii, v tom chisle novoi koronavirusnoi infektsii v epidemicheskom sezone 2020–2021gg. Postanovlenie Glavnogo gosudarstvennogo sanitarnogo vracha Rossiiskoi Federatsii ot 13.07.2020 no.20. https://www.rospotrebnadzor.ru/documents/details.php?ELEMENT_ID=15051 (in Russian).]
  19. О внесении изменения в приложение №1 к приказу Министерства здравоохранения Российской Федерации от 21.03.2014 №125н «Об утверждении национального календаря профилактических прививок и календаря профилактических прививок по эпидемическим показаниям». Приказ Министерства здравоохранения Российской Федерации от 14 сентября 2020 г. №967н. https://minzdrav.gov.ru/news/2020/10/13/15171-minzdrav-rossii-rasshiryaet-perechen-lits-podlezhaschih-vaktsinatsii-protiv-grippa-za-schet-sredstv-federalnogo-byudzheta http://publication.pravo.gov.ru/Document/View/0001202010120048?index=1&rangeSize=1 [O vnesenii izmeneniia v prilozhenie №1 k prikazu Ministerstva zdravookhraneniia Rossiiskoi Federatsii ot 21.03.2014 №125n “Ob utverzhdenii natsional’nogo kalendaria profilakticheskikh privivok i kalendaria profilakticheskikh privivok po epidemicheskim pokazaniiam”. Prikaz Ministerstva zdravookhraneniia Rossiiskoi Federatsii ot 14 sentiabria 2020 g. no.967n. https://minzdrav.gov.ru/news/2020/10/13/15171-minzdrav-rossii-rasshiryaet-perechen-lits-podlezhaschih-vaktsinatsii-protiv-grippa-za-schet-sredstv-federalnogo-byudzheta http://publication.pravo.gov.ru/Document/View/0001202010120048?index=1&rangeSize=1 (in Russian).]
  20. О ходе иммунизации населения против гриппа, об эпидемиологической ситуации по заболеваемости острыми респираторными вирусными инфекциями в мире и в Российской Федерации. Роспотребнадзор, 15 декабря 2020. https://www.rospotrebnadzor.ru/about/info/news/news_details.php?ELEMENT_ID=16273 [O khode immunizatsii naseleniia protiv grippa, ob epidemiologicheskoi situatsii po zabolevaemosti ostrymi respiratornymi virusnymi infektsiiami v mire i v Rossiiskoi Federatsii. Rospotrebnadzor, 15 dekabria 2020. https://www.rospotrebnadzor.ru/about/info/news/news_details.php?ELEMENT_ID=16273 (in Russian).]
  21. Гирина А.А., Петровский Ф.И., Заплатников А.Л. Приверженность врачей-педиатров иммунопрофилактике инфекционных болезней: современное состояние проблемы. РМЖ. Мать и дитя. 2020; 3 (4): 290–4. doi: 10.32364/2618-8430-2020-3-4-290–294 [Girina A.A., Petrovskii F.I., Zaplatnikov A.L. Priverzhennost’ vrachei-pediatrov immunoprofilaktike infektsionnykh boleznei: sovremennoe sostoianie problemy. RMZh. Mat’ i ditia. 2020; 3 (4): 290–4. doi: 10.32364/2618-8430-2020-3-4-290–294 (in Russian).]
  22. Amato M, Werba JP, Frigerio B et al. Relationship between Influenza Vaccination Coverage Rate and COVID-19 Outbreak: An Italian Ecological Study. Vaccines (Basel) 2020; 8 (3): 535. doi: 10.3390/vaccines8030535
  23. Marin-Hernandez D, Schwartz RE, Nixon DF. Epidemiological evidence for association between higher influenza vaccine uptake in the elderly and lower COVID-19 deaths in Italy. J Med Virol 2020; 1–2. doi: 10.1002/jmv.26120
  24. Zanettini C, Omar M, Dinalankara W еt al. Influenza Vaccination and COVID19 Mortality in the USA. medRxiv preprint 2020. doi: 10.1101/2020.06.24.2012981
  25. Arokiaraj МС. Correlation of influenza vaccination and the COVID-19 severity. SSRN 2020. doi: 10.2139/ssrn.3572814SSRN,2020
  26. Debisarun PA, Struycken P, Domínguez-Andrés J еt al. The effect of influenza vaccination on trained immunity: impact on COVID-19. Paper in collection COVID-19 SARS-CoV-2. medRx 2020. doi: 10.1101/2020.10.14.20212498

Supplementary files

Supplementary Files Action
1.
Fig. 1. Epidemic dynamics of daily detection of new patients with COVID-19 in China and the world (Rospotrebnadzor, 20.12.2020) [2].

Download (32KB) Indexing metadata
2.
Fig. 2. Candidate vaccines against COVID-19, approved for clinical trials (World Health Organization, 17.12.2020) [7].

Download (38KB) Indexing metadata
3.
Fig. 3. Vaccination against influenza and COVID-19 [23].

Download (59KB) Indexing metadata

Statistics

Views

Abstract - 7

PDF (Russian) - 0

Cited-By


Article Metrics

Metrics Loading ...

PlumX

Dimensions

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies