Why does it matter to the pediatrician whether the baby was born naturally or by Cesarean section? A review

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Abstract

Cesarean section is one of the most common operations in obstetrics and gynecology. However, despite the widespread use of this procedure, it is associated with certain risks for the mother and the child. As a result of cesarean section (CS), newborns do not acquire some important microorganisms during the passage of the maternal birth canal, which can impact the development and alter the functioning of the microbial ecosystem of the child. The gut microbiota plays an essential role in maintaining human health. It promotes digestion, strengthens the immune system, and produces some vitamins. Recent studies show that the intestinal microbiota of children born with CS differs from that of children born naturally. This article addresses the consequences of this difference on children's health and available ways of correcting the intestinal microbiota composition in children born via CS. Understanding the mechanisms of gut microbiota formation and function in these children can help develop effective strategies to prevent and treat various diseases associated with gut microbiota imbalance.

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About the authors

Irina N. Zakharova

Russian Medical Academy of Continuous Professional Education; Bashlyaeva Children’s City Clinical Hospital of the Moscow City Health Care Department

Author for correspondence.
Email: zakharova-rmapo@yandex.ru
ORCID iD: 0000-0003-4200-4598

Sci. (Med.), Prof.

Russian Federation, Moscow; Moscow

Yana V. Orobinskaya

Russian Medical Academy of Continuous Professional Education; Khimki Central Clinical Hospital

Email: zakharova-rmapo@yandex.ru
ORCID iD: 0009-0005-2121-4010

Graduate Student

Russian Federation, Moscow; Khimki

Irina V. Berezhnaya

Russian Medical Academy of Continuous Professional Education; Bashlyaeva Children’s City Clinical Hospital of the Moscow City Health Care Department

Email: berezhnaya-irina26@yandex.ru
ORCID iD: 0000-0002-2847-6268

Cand. Sci. (Med.)

Russian Federation, Moscow; Moscow

Narine G. Sugian

Russian Medical Academy of Continuous Professional Education; Mommy and Baby Outpatient clinic of Khimki Central Clinical Hospital

Email: narine6969@mail.ru
ORCID iD: 0000-0002-2861-5619

Cand. Sci. (Med.)

Russian Federation, Moscow; Khimki

Olga V. Dedikova

Russian Medical Academy of Continuous Professional Education

Email: olga.dedikova74@yandex.ru
ORCID iD: 0000-0002-3335-7124

pediatrician, Department Applicant

Russian Federation, Moscow

Svetlana I. Malyavskaya

Northern State Medical University

Email: zakharova-rmapo@yandex.ru
ORCID iD: 0000-0003-2521-0824

Sci. (Med.), Prof.

Russian Federation, Arkhangelsk

Daria M. Kurbakova

Northern State Medical University

Email: dde120600@mail.ru
ORCID iD: 0009-0002-2973-1256

Student

Russian Federation, Arkhangelsk

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