Collagenous enteritis as a rare cause of exudative enteropathy in a child. Case report
- Authors: Dmitrieva Y.A.1,2, Zakharova I.N.1, Zaplatnikov A.L.1, Radchenko E.R.2, Epifanova E.I.2, Abdurakhmanova L.S.3, Pokhvashcheva P.Y.4
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Affiliations:
- Russian Medical Academy of Continuous Professional Education
- Bashlyaeva Children’s City Clinical Hospital
- Children’s Medical Center, Moscow
- Pirogov Russian National Research Medical University
- Issue: No 2 (2024)
- Pages: 138-144
- Section: Articles
- URL: https://pediatria.orscience.ru/2658-6630/article/view/636969
- DOI: https://doi.org/10.26442/26586630.2024.2.202925
- ID: 636969
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Abstract
Exudative enteropathy (EE) syndrome can be associated with various diseases of the gastrointestinal tract (GIT) and is manifested by edematous syndrome, hypoproteinemia, hypoalbuminemia, lymphocytopenia, hypogammaglobulinemia, and an increase in the level of α-1-antitrypsin in the feces. More than 60 medical conditions are associated with loss of protein through the gastrointestinal tract, including erosive-ulcerative diseases of the gastrointestinal tract, non-erosive lesions of the mucous membrane causing an increase in the permeability of the intestinal wall, as well as disorders with an increase in pressure in the lymphatic system. Correct diagnosis and timely replacement and pathogenetic therapy are essential for the rapid cessation of pathological losses, the recovery of the proteinogram, and the prevention of life-threatening complications. Collagenous enteritis is one of the rare diseases of the small intestine associated with EE syndrome. The article presents a clinical case of a young child with EE and collagenous enteritis. The stages of the diagnostic workup in detecting EE syndrome in the child are discussed, and the pathogenetic factors that determined the development of this disorder are considered.
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About the authors
Yulia A. Dmitrieva
Russian Medical Academy of Continuous Professional Education; Bashlyaeva Children’s City Clinical Hospital
Author for correspondence.
Email: jadmitrieva@mail.ru
ORCID iD: 0000-0003-0668-7336
Cand. Sci. (Med.)
Russian Federation, Moscow; MoscowIrina N. Zakharova
Russian Medical Academy of Continuous Professional Education
Email: zakharova-rmapo@yandex.ru
ORCID iD: 0000-0003-4200-4598
D. Sci. (Med.), Prof.
Russian Federation, MoscowAndrey L. Zaplatnikov
Russian Medical Academy of Continuous Professional Education
Email: zaplatnikov@mail.ru
ORCID iD: 0000-0003-1303-8318
D. Sci. (Med.); Prof.
Russian Federation, MoscowElena R. Radchenko
Bashlyaeva Children’s City Clinical Hospital
Email: elen.radchenko@list.ru
ORCID iD: 0000-0001-5717-7171
Gastroenterologist
Russian Federation, MoscowElena I. Epifanova
Bashlyaeva Children’s City Clinical Hospital
Email: jadmitrieva@mail.ru
ORCID iD: 0000-0003-3795-3203
Pathologist
Russian Federation, MoscowLala S. Abdurakhmanova
Children’s Medical Center, Moscow
Email: lalina92@inbox.ru
ORCID iD: 0000-0001-6457-1193
Gastroenterologist
Russian Federation, MoscowPolina Y. Pokhvashcheva
Pirogov Russian National Research Medical University
Email: pokhvashcheva98@mail.ru
ORCID iD: 0000-0001-9983-6032
Resident
Russian Federation, MoscowReferences
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