Haemophilus influenzae infection in the practice of a pediatrician and pediatric surgeon. Case report

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Abstract

The paper discusses the issues of diagnosis, treatment, and prevention of surgical infection caused by Haemophilus influenzae type b (Hib) in children. Skin and soft tissue infections caused by Hib are potentially severe diseases and are associated with the risk of complications and disability in children. A clinical case of Hib infection in a 1-year-old child with a previous viral disease that triggered severe skin and soft tissue complications (necrosis of the right buttock soft tissues) is presented. Management included comprehensive treatment with modern non-surgical and surgical methods used in the clinical practice of a pediatric surgeon. Clinical experience shows that in some cases, antibiotics do not replace reasonable surgery, and in the treatment of children with generalized Haemophilus infection, surgical intervention should be a priority aimed at adequate early elimination of the suppurative focus.

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Liudmila I. Budkevich

Pirogov Russian National Research Medical University (Pirogov University); Speransky Pediatric City Clinical Hospital No. 9

Author for correspondence.
Email: mila-budkevich@yandex.ru
ORCID iD: 0000-0002-8975-6108

D. Sci. (Med.), Prof.

 

Russian Federation, Moscow; Moscow

Vera V. Soshkina

Speransky Pediatric City Clinical Hospital No. 9

Email: mila-budkevich@yandex.ru
ORCID iD: 0000-0002-8605-8670

Cand. Sci. (Med.)

Russian Federation, Moscow

References

  1. Васильев В.С., Кравчук Ю.В., Васильев А.В. Гемофильная инфекция. Журнал Гродненского государственного медицинского университета. 2012;4:82-5 [Vasil'ev VS, Kravchuk IuV, Vasil'ev AV. Gemofil'naia infektsiia. Zhurnal Grodnenskogo gosudarstvennogo meditsinskogo universiteta. 2012;4:82-5 (in Russian)].
  2. Абрамцева М.В., Тарасов А.П., Немировская Т.И., и др. Гемофильная инфекция типа b. Заболеваемость и вакцинопрофилактика. БИОпрепараты. Профилактика, диагностика, лечение. 2017;17(2):78-86 [Abramtseva MV, Tarasov AP, Nemirovskaya TI, et al. Haemophilus influenza type b. Incidence rate and preventive vaccination. BIOpreparations. Prevention, Diagnosis, Treatment. 2017;17(2):78-86 (in Russian)].
  3. Invasive Haemophilus influenzae in Europe FU-IBIS Network. Health Protection Agency, London 2006.
  4. Platonov AE, Griffiths UK, Voeykova MV, et al. Economic evaluation of Haemophilus influenzae type b vaccination in Moscown Federation. Vaccine. 2006;24(13):2367-76.
  5. Bennett JV, Platonov AE, Slack MPE, et al. Haemophilus influenzae type b (Hib) meningitis in the pre-vaccine era: a global review of incidence, age distribution, and case-fatality rates. Document WHO/V&B/02.18. Geneva, World Health Organization, 2002.
  6. Баранов А.А., Горелов А.А., Задорожная В.И., и др. Современное состояние проблемы Hib-инфекции в Беларуси, Казахстане, России и Украине. Вопросы современной педиатрии. 2006;5(2):6-11 [Baranov AA, Gorelov AA, Zadorozhnaia VI, et al. Sovremennoe sostoianie problemy Hib-infektsii v Belarusi, Kazakhstane, Rossii i Ukraine. Voprosy sovremennoi pediatrii. 2006;5(2):6-11 (in Russian)].
  7. Платонов А.Е., Королева И.С., Платонова О.В., Покровский В.И. и Московская группа по исследованию гемофильных менингитов. Заболеваемость гнойными бактериальными менингитами у детей в возрасте до 5 лет в Москве. Эпидемиология и инфекционные болезни. 2006;(4):36-43 [Platonov AE, Koroleva IS, Platonova OV, Pokrovskii VI; Moskovskaia gruppa po issledovaniiu gemofil'nykh meningitov. Zabolevaemost' gnoinymi bakterial'nymi meningitami u detei v vozraste do 5 let v Moskve. Epidemiologiia i infektsionnye bolezni. 2006;(4):36-43 (in Russian)].
  8. Платонов А.Е., Николаев М.К. Заболеваемость гнойными менингитами у детей в возрасте до 5 лет в регионах России. Эпидемиология и инфекционные болезни. 2007;3:10-8.
  9. Платонов А.Е., Николаев М.К., Королева И.С., и др. Проспективное популяционное изучение заболеваемости гнойными менингитами у детей в возрасте до 5 лет в 8 городах России. Эпидемиология и инфекционные болезни. 2009;(4):133-43 [Patonov AE, Nikolaev MK, Koroleva IS, et al. Prospektivnoe populiatsionnoe izuchenie zabolevaemosti gnoinymi meningitami u detei v vozraste do 5 let v 8 gorodakh Rossii. Epidemiologiia i infektsionnye bolezni. 2009;(4):133-43 (in Russian)].
  10. Казанцев А.П. Гемофильная инфекция. В кн.: Руководство по инфекционным болезням. Под ред. Ю.В. Лобзина, А.П. Казанцева. СПб.: Комета, 1996 [Kazantsev AP. Gemofil'naia infektsiia. In: Rukovodstvo po infektsionnym bolezniam. Pod red. IuV Lobzina, AP Kazantseva. Saint Petersburg: Kometa, 1996 (in Russian)].
  11. Chandran A, Watt JP, Santosham M. Haemophilus influenzae vaccines. In: Plotkin SA, Orenstein WA, eds. Vaccines. 5th ed. Philadelphia, PA: WB Saunders Co., 2008; p. 157-76.
  12. Pittman M. Variation and type specificity in the bacterial species Haemophilus influenzae. J Exp Med. 1931;53:471-92.
  13. WHO position paper on Haemophilus influenzae type b conjugate vaccines. Weekly Epidemiological Record. 2006;81(47):445-52.
  14. Spinola SM, Peacock J, Denny FW, et al. Epidemiology of colonization with nontypable Haemophilus influenza in children: A longitudinal study. J Infect Dis. 1986;154:100-9.
  15. Orenstein W, Wharton M, Bart KJ, Hinman AR. Immunization. In: Mandell GL, Bennett JE, Dolin R, ed. Principles and practice of infectious diseases. 5th ed. Churchill Livingstone, 2000; p. 3213-4.
  16. Fuchs PC, Barry AL. Interpretative criteria for susceptibilities of Haemophilus influenza to ampicillin, amoxicillin and amoxicillin/clavulanate. J Clin Microbiol. 1994;32:2846-50.
  17. Будкевич Л. И., Сошкина В. В., Астамирова Т. С., и др. Современные перевязочные средства в комбустиологии детского возраста. Российский вестник детской хирургии, анестезиологии и реаниматологии. 2018;8(4):48-57.
  18. Orenstein W, Wharton M, Bart KJ, Hinman AR. Immunization. In: Mandell GL, Bennett JE, Dolin R, ed. Principles and practice of infectious diseases. 5th ed. Churchill Livingstone, 2000; p. 3213-4.
  19. Rossi IA, Zuber PL, Dumolard L, et al. Introduction of Hib-vaccine into national immunization programmes: a descriptive analysis of global trends. Vaccine. 2007;25(41):7075-80.

Supplementary files

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2. Fig. 1. Abnormal changes in the skin in the right gluteal region.

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3. Fig. 2. Right gluteal region on admission to the burn ward.

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4. Fig. 3. Necrotic tissues in the right gluteal region before surgery and after debridement (day 9 of the disease).

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5. Fig. 4. Wounds during treatment.

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6. Fig. 5. Wound on day 14 of vacuum therapy.

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7. Fig. 6. Staged surgical intervention: hydrosurgical wound treatment with the "VersaJet" device, autodermoplasty with a free split skin autograft with 1:3 perforations.

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8. Fig. 7. Dressing change on day 6 after autodermoplasty.

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