Etiology and features of the course of the wound process in neonates

Cover Page

Cite item


Introduction. Despite the significant progress made in recent decades in reducing the mortality rate, the risks of adverse outcomes in infectious and inflammatory soft tissue diseases in newborns are still high. The high-risk group consists of children from mothers with a pre-morbid background, as well as premature infants with intrauterine hypoxia and intracranial birth trauma. Traumatization and infection can also occur during medical manipulations (tracheal intubation, vascular catheterization, damage to the baby’s skin during obstetrical procedures, etc.). The variety of pathological processes that cause wounds of different etiology is due to the anatomical and physiological features of the skin of newborns. In addition, neonatal skin lesions may be a manifestation of systemic diseases and may themselves be the cause of manifestation.

Materials and methods. Medical records of 147 neonates treated in infectious and burn units of Speransky Children’s City Clinical Hospital №9 were analyzed. Clinical examples of children in the first month of life with wounds of various etiologies are presented.

Conclusion. Treatment of newborn infants with inflammatory processes of the skin and underlying tissues of different etiology requires multidisciplinary approach with the involvement of not only surgical specialists.

Full Text

Restricted Access

About the authors

Anna A. Avanesyan

Speransky Children’s City Clinical Hospital №9

Author for correspondence.
ORCID iD: 0000-0003-1565-9003

paediatric surgeon

Russian Federation, Moscow

Tatiana S. Astamirova

Speransky Children’s City Clinical Hospital №9


paediatric surgeon

Russian Federation, Moscow

Liudmila I. Budkevich

Speransky Children’s City Clinical Hospital №9; Pirogov Russian National Research Medical University


D. Sci. (Med.), Prof.

Russian Federation, Moscow; Moscow


  1. Jurica SA, Čolić A, Gverić-Ahmetašević S, et al. Skin of the very premature newborn – physiology and care. Paediatr Croat 2016; 60: 21–6. doi: 10.13112/PC.2016.4
  2. Cousins Y. Wound care considerations in neonates. Nursing Standard 2014; 28 (46); 61–70. doi: 10.7748/ns.28.46.61.e8402
  3. Neonatal skin and wound care. Brighton and Sussex University Hospitals. 2018. Available at: Accessed: 25.04.2021.
  4. Bhatt MD, Ho K, Chan AKC. Disorders of coagulation in the neonate. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2018.
  5. Румянцев А.Г., Масчан А.А., Жарков П.А., Свирин П.В. Федеральные клинические рекомендации по диагностике, лечению и профилактике тромбозов у детей и подростков. М., 2015 [Rumiantsev AG, Maschan AA, Zharkov PA, Svirin PV. Federal clinical recommendations on diagnosis, treatment and prevention of thrombosis in children. Moscow, 2015 (in Russian)].
  6. Bendapudi PK, Robbins A, LeBoeuf N, et al. Persistence of endothelial thrombomodulin in a patient with infectious purpura fulminans treated with protein C concentrate. Blood Adv 2018; 2 (21): 2917–21. doi: 10.1182/bloodadvances.2018024430
  7. Ильина Я.Ю., Фот Е.В., Кузьков В.В., Киров М.Ю. Сепсис-индуцированное повреждение эндотелиального гликокаликса (обзор литературы). Вестник интенсивной терапии им. А.И. Салтанова. 2019; 2: 32–9 [Ilina IaIu, Fot EV, Kuzkov VV, Kirov MIu. Sepsis-indutsirovannoe povrezhdenie endotelialnogo glikokaliksa (obzor literatury). Vestnik intensivnoi terapii im. A.I. Saltanova 2019; 2: 32–9 (in Russian)]. doi: 10.21320/1818-474X-2019-2-32-39.

Supplementary files

Supplementary Files
1. Fig. 1. The girl, 7 days old: a – burn of the 2–3rd degree of hot fluid in the right side of the face in the area of 3% of body surface; b – view of the wound on the 3rd day after the injury before surgical necrectomy; c – wound surface after removal of necrotic tissue (3rd day); d – the forming hypertrophic scar 1 month after the injury.

Download (905KB)
2. Fig. 2. The boy A., 14 days old: a – soft tissue necrosis in the left forearm; b – wound appearance on the 8th day; c – complete wound epithelialization after local conservative treatment (16th day).

Download (681KB)
3. Fig. 3. Boy, 8 days old: a – dry gangrene of the right hand (3 days); b – dry gangrene of the left hand (3 days); c –7-day postoperative intervention (necrectomy, exarticulation).

Download (830KB)
4. Fig. 4. The infant born at term with a birth weight of 3800 g: a – areas of hemorrhagic necrosis in the lower extremities, in the crotch (3 days of life); b – wounds after partial detachment of devitalized tissues (21 days of life); c – type of granulation wounds after removal of dry crust (23 days of life); d – complete epithelialization of the wounds on the 28th day of hospital treatment.

Download (910KB)

Copyright (c) 2021 Consilium Medicum

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 74329 от 19.11.2018 г.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies