Impact of gut microbiota and vitamin A and D supplementation on child health

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The influence of nutrients on the development and health of a child from its prenatal development and throughout its life is discussed now. Particular attention is paid to maternal nutrition, the presence of breastfeeding, the intake of supplements such as vitamin D and probiotics. It is known that the composition of the intestinal microbiota of the newborn child is negatively affected by the mother’s taking antibiotics during pregnancy or in the early neonatal period, which affects the development of the infant’s immune system, contributes to atopic diseases, including atopic dermatitis and bronchial asthma, increases the risk of obesity and metabolic syndrome, Crohn’s disease, type 1 diabetes, etc. Differences in the microbiota are particularly significant after antibiotic therapy for emergency caesarean section. Studies have shown that it is possible to normalise the microbiota during the 1st year of life in exclusively breastfed infants. The synergism of probiotic strains of gut microbiota and vitamin D is discussed in the scientific literature.

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About the authors

Irina N. Zakharova

Russian Medical Academy of Continuous Professional Education

Author for correspondence.
ORCID iD: 0000-0003-4200-4598

D. Sci. (Med.), Prof.

Russian Federation, Moscow

Olga V. Dedikova

Russian Medical Academy of Continuous Professional Education


Clinical Resident

Russian Federation, Moscow

Anastasiia E. Kuchina

Russian Medical Academy of Continuous Professional Education


Graduate Student

Russian Federation, Moscow

Aleksandra I. Sgibneva

Pirogov Russian National Research Medical University



Russian Federation, Moscow


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Supplementary files

Supplementary Files
1. Schematic representation of the assimilation of nutrients by the gut microbiome and their effects on the distal organs [20].

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