The accumulation of glycogen in neutrophilic granulocytes in children with glycogen disease

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Abstract

Glycogen metabolism disorder due to genetic inherited defects is a rare disorder leading to pathological accumulation of the substance in liver, muscle tissue. Due to the expansion of genetic testing, it is possible to confirm the diagnosis and determine the type of glycogen storage disease. Here is a clinical example of type X glycogen disease in a 4-year-old girl.

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About the authors

Olesia V. Pervichko

Kuban State Medical University

Author for correspondence.
Email: ole-pervishko@yandex.ru

Cand. Sci. (Med.)

Russian Federation, Krasnodar

Natalia G. Soboleva

Clinic “G8 Center”

Email: pervishko@yandex.ru

D. Sci. (Med.), Prof.

Russian Federation, Krasnodar

Andrei A. Evglevsky

Kuban State Medical University

Email: pervishko@yandex.ru

Cand. Sci. (Med.)

Russian Federation, Krasnodar

Tamara G. Baum

Kuban State Medical University

Email: pervishko@yandex.ru

Cand. Sci. (Med.)

Russian Federation, Krasnodar

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Supplementary files

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1. Fig. 1. Girl 4 years old with glycogen type X disease.

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2. Fig. 2. Glycogen in neutrophilic granulocytes in a child with glycogen disease Х type (Schick reaction by McManus).

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