The results of monitoring children with a new coronavirus infection, hospitalized in the infectious diseases department

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Abstract

Aim. The analysis the clinical, laboratory and instrumental data and the results of therapy of children hospitalized with the new coronavirus infection in the infectious clinic hospital.

Materials and methods. The analysis of the clinical course of the disease was carried out in 105 children aged 1 month to 17 years with confirmed COVID-19 infection, hospitalized in the infectious diseases hospital of the clinic. The examination included physical examination, determination of ferritin, coagulogram, IL-6, markers of bacterial infection – procalcitonin and C-reactive protein, PCR diagnostics for detecting SARS-CoV-2 RNA in swabs from the nasopharynx and oropharynx, microbiological examination of nasal swabs and pharynx, pulse oximetry, computed tomography of the chest organs, specialist consultations according to indications.

Results and discussion. A large proportion of the patients were school-age boys. The etiology of the disease caused by the SARS-CoV-2 virus was confirmed by PCR. It was found that more often the disease was accompanied by complaints characteristic of asthenic syndrome, fever and cough. The main clinical forms of the disease were acute viral infection and pneumonia without respiratory failure of moderate severity. In most children, the infection proceeded without damage to the lung tissue or with minimal damage to the lung parenchyma. A more severe course of infection with the development of respiratory failure was noted in schoolchildren and adolescents. In 42.9% of children were revealed multimorbid conditions. The most common conditions were iron deficiency anemia and autonomic dysfunction. The most severe course of infection was noted in children with hematological malignancies. In laboratory tests, children showed leukopenia, an increase of ferritin and activation of thrombus formation. 51.4% children were discharged in 11–14 days of the disease. Deaths were in 1.9% of patients with leukemia.

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About the authors

Natalia V. Samigullina

Bashkir State Medical University; Ufa Emergency Hospital

Author for correspondence.
Email: samigullinanw@gmail.com
ORCID iD: 0000-0003-3415-0595

Cand. Sci. (Med.), Bashkir State Medical University

Russian Federation, Ufa; Ufa

Rezeda M. Faizullina

Bashkir State Medical University

Email: fayzullina@yandex.ru
ORCID iD: 0000-0002-9001-1437

D. Sci. (Med.), Prof., Bashkir State Medical University

Russian Federation, Ufa

Vitalii V. Viktorov

Bashkir State Medical University

Email: surgped@bashgmu.ru
ORCID iD: 0000-0001-5260-2319

D. Sci. (Med.), Prof., Bashkir State Medical University

Russian Federation, Ufa

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Supplementary files

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2. Fig. 1. Age structure of children hospitalized with new coronavirus infection.

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3. Fig. 2. Clinical symptoms in children hospitalized with new coronavirus infection.

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4. Fig. 3. The area of lung tissue lesions in children hospitalized with new coronavirus infection.

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5. Fig. 4. The structure of the clinical forms of the disease in children hospitalized with new coronavirus infection.

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6. Fig. 5. Structure by the severity of the disease in children hospitalized with new coronavirus infection.

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7. Fig. 6. The structure of children hospitalized with COVID-19 in terms of severity and clinical forms in terms of age.

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