Probiotics as prevention for gastro-intestinal disorders in pediatrics


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Abstract

The gastro-intestinal microbiome is a hot topic in clinical research. Beneficial effects of selected probiotics in the prevention of gastrointestinal disorders are mainly limited to acute gastroenteritis, antibiotic-associated diarrhea, infantile colic and necrotizing enterocolitis. However, there is no broad consensus to recommend the use of probiotics in the prevention of these conditions, mainly because of the different design of the multiple studies, resulting in a limited evidence for specific strains and dosages and indications. More well-designed studies are needed before recommendations can be proposed. At this stage, there is insufficient evidence to recommend the routine use of probiotics in infants and children for the prevention of gastro-intestinal disorders.

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About the authors

Celine Perceval

KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel

Brussels, Belgium

Michel Pletincx

CHIREC, St-Anne St-Remi

Brussels, Belgium

Yvan Vandenplas

KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel

Email: yvan.vandenplas@uzbrussel.be
Brussels, Belgium

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