Пробиотики для профилактики гастроинтестинальных расстройств у детей: обзор научных данных


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Микробиом желудочно-кишечного тракта остается актуальной областью для клинических исследований. Данные о положительных эффектах отдельных пробиотиков в профилактике гастроинтестинальных расстройств ограничиваются исследованиями в отношении острого гастроэнтерита, антибиотикоассоциированной диареи, младенческих колик и некротизирующего энтероколита. Общий консенсус, рекомендующий использование пробиотиков при указанных состояниях, отсутствует, что обусловлено разным дизайном большинства работ, недостаточным объемом доказательств в отношении определенных штаммов, дозировок и показаний. Для формирования однозначных рекомендаций требуется большее количество хорошо спланированных исследований. На данном этапе доказательств, определяющих целесообразность рутинного использования пробиотиков для профилактики гастроинтестинальных расстройств у детей, недостаточно.

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Ц. Перцевал

Университетская клиника Брюсселя, Свободный университет Брюсселя

Брюссель, Бельгия

М. Плетинцх

Группа CHIREC, клиника Ste-Anne St-Remi

Брюссель, Бельгия

Иван Ванденплас

Университетская клиника Брюсселя, Свободный университет Брюсселя

Email: yvan.vandenplas@uzbrussel.be
д-р мед. наук, проф., зав. отд-нием педиатрии Брюссель, Бельгия

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