Questions of systemic and topical antibacterial therapy of acute rhinosinusitis in a child

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Background. Acute otitis media is the most common complication of acute respiratory viral infection in children under 6 years of age. More than 90% of children suffer from acute otitis media in the first 5 years of life. Ear pain is one of the main symptoms of acute otitis media and determines the patient's well-being.

Aim. To evaluate the efficacy and tolerability of the use of ear drops based on the combination of phenazone and lidocaine in the local therapy of acute otitis media in the preperforative stage in children.

Materials and methods. A retrospective analysis of the outpatient records of 50 patients with complaints of symptoms of acute otitis media was performed.

Results. Based on the analysis of medical records, it was found that the use of ear drops based on a combination of phenazone and lidocaine can significantly reduce the severity of ear pain in acute otitis media within 3 minutes. The use of ear drops based on the combination of phenazone and lidocaine for a course of 7 days allows most patients to abandon the use of systemic forms of analgesics. No patient has been reported to have developed adverse events associated with the use of phenazone-lidocaine combination ear drops.

Conclusion. The use of ear drops based on a fixed combination of lidocaine + phenazone is not only a highly effective and safe drug for the treatment of acute otitis media in the preperforative stage in children, but also a fast symptomatic therapy, which physicians after otoscopy can use as the method of choice to reduce patients' ear pain already during the initial examination.

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Elena Karpova

Russian Medical Academy of Continuous Professional Education

Email: edoctor@mail.ru
ORCID iD: 0000-0002-8292-9635

D. Sci. (Med.), Prof., Russian Medical Academy of Continuous Professional Education

俄罗斯联邦, Moscow

Denis Tulupov

Russian Medical Academy of Continuous Professional Education; Filatov Children's City Clinical Hospital

编辑信件的主要联系方式.
Email: tulupov-rmapo@yandex.ru
ORCID iD: 0000-0001-6096-2082

Cand. Sci. (Med.), Assoc. Prof., Russian Medical Academy of Continuous Professional Education, Filatov Children's City Clinical Hospital

俄罗斯联邦, Moscow; Moscow

Maria Emel'yanova

Russian Medical Academy of Continuous Professional Education; Family Clinic “Healthy Children”

Email: tulupov-rmapo@yandex.ru

Senior Assistant, Russian Medical Academy of Continuous Professional Education, Family Clinic “Healthy Children”

俄罗斯联邦, Moscow; Lytkarino

Oleg Naumov

Russian Medical Academy of Continuous Professional Education; Filatov Children's City Clinical Hospital

Email: olegnaumov.68@mail.ru
ORCID iD: 0000-0002-8243-8385

Cand. Sci. (Med.), Russian Medical Academy of Continuous Professional Education, Filatov Children's City Clinical Hospital

俄罗斯联邦, Moscow; Moscow

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2. Fig. 1. The change of ear pain during the treatment with the reference medication ear drops based on a fixed dose combination of lidocaine + phenazone to control pain at the primary doctor's visit.

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3. Fig. 2. Severe otoscopic changes in acute catarrhal otitis media at the initial presentation.

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4. Fig. 3. Local otoscopic changes in acute catarrhal otitis media. The otoscopic picture is typical for days 3–4 of using ear drops based on a fixed dose combination of lidocaine + phenazone.

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5. Fig. 4. Otoscopic picture of convalescence of acute catarrhal otitis media.

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6. Fig. 5. The course of inflammation in the eardrum during the use of ear drops based on a fixed dose combination of lidocaine + phenazone.

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