Relationship between atopic dermatitis and food allergy

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Atopic dermatitis (AD) is often associated with food allergies. The development of food allergies can worsen the course of AD. The increase in the incidence of AD and food intolerance may be associated with changes in the epigenome under the influence of the environment. There are also many prenatal and perinatal factors that can increase the risk of developing food allergies and/or AD: changes in the intestinal microbiota of the mother during pregnancy, caesarean section, the season of childbirth, etc. In the postnatal period, changes in the composition of the microbiome become important risk factors for the development of these diseases. exposure to food allergens. As shown by our own observations, depending on the age group, the set of food allergens may change and play a lesser role in exacerbation of AD. In cases where an allergic component acts as a provoking factor for AD, an antihistamine must be included in the therapy. Our experience shows the effectiveness of the use of desloratadine in pediatric practice together with topical glucocorticosteroids and moisturizers.

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About the authors

Olga lu. Smolkina

Scientific and Clinical Advisory Center for Allergology and Immunology

Evgeniia V. Dvoriankova

Center for Theoretical Problems of Physicochemical Pharmacology


Zofiia A. Nevozinskaia

Moscow Scientific and Practical Center for Dermatovenereology and Cosmetology

Irina M. Korsunskaia

Center for Theoretical Problems of Physicochemical Pharmacology


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