Visceral leishmaniasis in children (own results and literature analysis)


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Abstract

Leishmaniasis is a tropical parasitic infection with a preferred lesion in children. Leishmaniasis, perceived as an infection in hot and humid regions, is not always taken into account in the differential diagnostic search in febrile children with splenomegaly, the degree of which prevails over hepatic anemia. The geographical factor is not taken into account. In our observations, the period from the first symptoms to the diagnosis ranged from 0.5 to 17 months. The diagnosis is confirmed by the results of bone marrow puncture, immunological tests. Treatment is based on the use of antimony drugs. Often, adverse reactions are recorded in the form of an increase in hepatic enzymes, bilirubinemia, anemia. Prevention is the avoiding of mosquito bites.

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About the authors

Galina I. Volkova

Dmitry Rogachev National Medical Research Center of Pediatric Hematology; Russian Children's Clinical Hospital, Pirogov Russian National Research Medical University

Moscow, Russia

Mariia I. Smirnova

Dmitry Rogachev National Medical Research Center of Pediatric Hematology

Moscow, Russia

Wassili M. Delyagin

Dmitry Rogachev National Medical Research Center of Pediatric Hematology

Email: delyagin-doktor@yandex.ru
Moscow, Russia

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