Alcohol consumption and dyslipidemia in children and adolescents: A review

Cover Page

Cite item

Full Text

Abstract

Consumption of low-alcohol products by young people is due to the erroneous opinion that they are safe for health. However, against the background of taking low-alcohol drinks, addiction quickly forms and complications develop, including lipid metabolism disorders. Studies show that consumption of low-concentration ethanol-containing drinks changes the structure and ratio of serum lipoproteins. Changes in serum lipids provoked by alcohol intake are involved in the pathogenesis of a number of chronic non-infectious diseases, including alcoholic fatty liver disease and atherosclerotic cardiovascular diseases. According to the data of an anonymous online survey, which involved 155 young people aged 17–20 (18±0.76) years, 17.4% of them consume low-concentration alcohol more than once a week, and 5.8% consume both low-alcohol drinks and strong alcohol daily. Comprehensive efforts are needed to prevent the spread of alcohol addiction among children and young people: raising the age at which it is possible to purchase alcoholic beverages, increasing penalties in the area of illegal alcohol trafficking, and working in the area of anti-alcohol propaganda.

Full Text

Restricted Access

About the authors

Irina I. Pshenichnikova

Russian Medical Academy of Continuous Professional Education

Email: PshenichnikovaII@rmapo.ru
ORCID iD: 0000-0002-0058-3803

Cand. Sci. (Med.)

Russian Federation, Moscow

Viktoria V. Pupykina

Russian Medical Academy of Continuous Professional Education

Email: vika-pupykina@mail.ru
ORCID iD: 0000-0003-2181-8138

Graduate Student

Russian Federation, Moscow

Arina D. Pshenichnikova

Moscow Polytechnic University

Email: chilipidra@gmail.com
ORCID iD: 0009-0005-2255-7154

Student

Russian Federation, Moscow

Irina N. Zakharova

Russian Medical Academy of Continuous Professional Education

Author for correspondence.
Email: zakharova-rmapo@yandex.ru
ORCID iD: 0000-0003-4200-4598

D. Sci. (Med.), Prof.

Russian Federation, Moscow

References

  1. Продукция слабоалкогольного и безалкогольного производства. Термины и определения. ГОСТ 34792-2021. Режим доступа: https://gostassistent.ru/doc/b2b99483-8e0f-462f-9008-6119bffb6bdf. Ссылка активна на 08.08.2024 [Produktsiia slaboalkogol’nogo i bezalkogol’nogo proizvodstva. Terminy i opredeleniia. GOST 34792-2021. Available at: https://gostassistent.ru/doc/b2b99483-8e0f-462f-9008-6119bffb6bdf. Accessed: 08.08.2024 (in Russian)].
  2. Позднякова М.Е. Алкогольные традиции в современной России. Фундаментальные аспекты психического здоровья. 2015;3:36-45 [Pozdniakova ME. Alkogol’nye traditsii v sovremennoi Rossii. Fundamental’nye Aspekty Psikhicheskogo Zdorov’ia. 2015;3:36-45 (in Russian)].
  3. Kalinowski A, Humphreys K. Governmental standard drink definitions and low-risk alcohol consumption guidelines in 37 countries. Addiction. 2016;111(7):1293-8. doi: 10.1111/add.13341
  4. Кошкина Е.А., Киржанова В.В., Павловская Н.И., и др. Особенности употребления алкоголя среди молодежи в России на современном этапе. Наркология. 2007;1;19-23 [Koshkina EA, Kirzhanov VV, Pavlovskay NI, et al. Alcohol use among youth of Russia at the present moment. Narcology. 2007;1;19-23 (in Russian)].
  5. Селиванова О.А., Быстрова Н.В., Панфилова О.В. Исследование зависимости подростков от слабоалкогольных напитков. Международный журнал медицины и психологии. 2020;3(2):28-33 [Selivanova OA, Bystrova NV, Panfilova OV. The research of teenager’s addiction to low-alcoholic drinks. International Journal of Medicine and Psychology. 2020;3(2):28-33 (in Russian)].
  6. Inchley J, Currie D, Budisavljevic S, et al., eds. Spotlight on adolescent health and well-being. Findings from the 2017/2018 Health Behaviour in School-aged Children (HBSC) survey in Europe and Canada. International report. Vol. 2. Key data. Available at: https://iris.who.int/bitstream/handle/10665/332104/9789289055017-eng.pdf?sequence=1&isAllowed=y. Accessed: 08.08.2024.
  7. Кондратенко В.А. Структура и типы потребления алкоголя российской молодежью и их родителями в 2006–2019 гг. Вестник Российского мониторинга экономического положения и здоровья населения НИУ ВШЭ (RLMS-HSE). М.: Национальный исследовательский университет «Высшая школа экономики», 2022. Вып. 12, гл. 5 [Kondratenko VA. Struktura i tipy potrebleniia alkogolia rossiiskoi molodezh’iu i ikh roditeliami v 2006–2019 gg. Vestnik Rossiiskogo monitoringa ekonomicheskogo polozheniia i zdorov’ia naseleniia NIU VShE (RLMS-HSE). Moscow: Natsional’nyi issledovatel’skii universitet «Vysshaia shkola ekonomiki», 2022. Vyp. 12, gl. 5 (in Russian)]. doi: 10.19181/rlms-hse.2022.5
  8. Charrier L, van Dorsselaer S, Canale N, et al. A focus on adolescent substance use in Europe, central Asia and Canada. Health Behaviour in School-aged Children international report from the 2021/2022 survey. Vol. 3. Copenhagen: WHO Regional Office for Europe, 2024. Available at: https://www.who.int/europe/publications/i/item/9789289060936. Accessed: 08.08.2024.
  9. Ventura-Cots M, Ballester-Ferré MP, Ravi S, Bataller R. Public health policies and alcohol-related liver disease. JHEP Rep. 2019;1(5):403-13. doi: 10.1016/j.jhepr.2019.07.009
  10. Ojeda ML, Nogales F, Del Carmen Gallego-López M, Carreras O. Binge drinking during the adolescence period causes oxidative damage-induced cardiometabolic disorders: A possible ameliorative approach with selenium supplementation. Life Sci. 2022;301:120618. doi: 10.1016/j.lfs.2022.120618
  11. Bullock C. The biochemistry of alcohol metabolism – A brief review. Biochemical Education. 1990;18(2):62-6.
  12. Zakhari S. Overview: How is alcohol metabolized by the body? Alcohol Res Health. 2006;29(4):245-54. PMID: 17718403
  13. Binder C, Knibbe K, Kreissl A, et al. Does acute alcohol intoxication cause transaminase elevations in children and adolescents? Alcohol. 2016;51:57-62. doi: 10.1016/j.alcohol.2015.12.001
  14. Latour MA, Patterson BW, Kitchens RT, et al. Effects of alcohol and cholesterol feeding on lipoprotein metabolism and cholesterol absorption in rabbits. Arterioscler Thromb Vasc Biol. 1999;19(3):598-604. doi: 10.1161/01.atv.19.3.598
  15. Bessembinders K, Wielders J, van de Wiel A. Severe hypertriglyceridemia influenced by alcohol (SHIBA). Alcohol Alcohol. 2011;46(2):113-6. doi: 10.1093/alcalc/agq088
  16. Kwon YJ, Kim SE, Park BJ, et. al. High-risk drinking is associated with dyslipidemia in a different way, based on the 2010–2012 KNHANES. Clin Chim Acta. 2016;456:170-5. doi: 10.1016/j.cca.2016.03.009
  17. Tanisawa K, Ito T, Kawakami R, et al. Association between alcohol dietary pattern and prevalence of dyslipidaemia: WASEDA’S Health Study. Br J Nutr. 2022;127(11):1712-22. doi: 10.1017/S0007114521002671
  18. Wang Z, Yao T, Song Z. Chronic alcohol consumption disrupted cholesterol homeostasis in rats: Down-regulation of low-density lipoprotein receptor and enhancement of cholesterol biosynthesis pathway in the liver. Alcohol Clin Exp Res. 2010;34(3):471-8. doi: 10.1111/j.1530-0277.2009.01111.x
  19. Hong SW, Linton JA, Shim JY, Kang HT. High-risk drinking is associated with a higher risk of diabetes mellitus in Korean men, based on the 2010–2012 KNHANES. Alcohol. 2015;49(3):275-81. doi: 10.1016/j.alcohol.2015.02.004
  20. Morrison JA, Kelly K, Mellies M, et al. Cigarette smoking, alcohol intake, and oral contraceptives: Relationships to lipids and lipoproteins in adolescent school-children. Metabolism. 1979;28(11):1166-70. doi: 10.1016/0026-0495(79)90157-4
  21. Tung YC, Hsiao FC, Lin CP, et al. High triglyceride variability increases the risk of first attack of acute pancreatitis. Am J Gastroenterol. 2023;118(6):1080-90. doi: 10.14309/ajg.0000000000002198
  22. Васильев А.П., Стрельцова Н.Н. Алкоголь и сердце. РМЖ. 2018;26(1-2):82-5 [Vasiliev AP, Streltsovа NN. Alcohol and heart disease. RMJ. 2018;26(1-2):82-5 (in Russian)].

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2024 Consilium Medicum

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 74329 от 19.11.2018 г.