The positive effect of ω-3 polyunsaturated fatty acid supplementation on the cognitive function of children and adolescents with lipid metabolism disorders

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Abstract

Aim. To study the effect of ω-3 polyunsaturated fatty acids (PUFAs) on the cognitive functions of children with lipid metabolism disorders of different ages.

Materials and methods. The study included 87 children aged 6 to 17 years who had not previously received ω-3 PUFA supplements. All subjects were tested twice, with an interval of 6 months, to determine the ω-3 erythrocyte index by gas chromatography-mass spectrometry and to study attention span and focusing using the correction task method (Bourdon test). The cohort was randomly divided into two groups: the main group, which included 60 children who received the ω-3 supplements, and the control group, which included 27 children who did not receive any nutritional supplements.

Results. In children of the main group, after receiving the Norwegian fish oil NFO® at 1000 mg for 6 months, an increase in the erythrocyte ω-3 index was observed, while in the control group, it did not change significantly. A statistically significant correlation was found between the adequacy of ω-3 PUFA and the attention span and focusing.

Conclusion. The results of the study showed the effectiveness of ω-3 PUFA supplementation at 1000 mg/day for 6 months and confirmed the positive effect of ω-3 PUFA on the cognitive sphere of children and adolescents. High-quality food supplements with ω-3 PUFAs at 1000 mg/day can be recommended to develop intellection, memory, and attention span and focus in children and adolescents.

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About the authors

Irina N. Zakharova

Russian Medical Academy of Continuous Professional Education

Email: zakharova-rmapo@yandex.ru
ORCID iD: 0000-0003-4200-4598

D. Sci. (Med.), Prof.

Russian Federation, Moscow

Iuliya V. Korchagina

Russian Medical Academy of Continuous Professional Education

Email: zakharova-rmapo@yandex.ru

Resident

Russian Federation, Moscow

Irina I. Pshenichnikova

Russian Medical Academy of Continuous Professional Education

Author for correspondence.
Email: shenichnikovaII@rmapo.ru
ORCID iD: 0000-0002-0058-3803

Cand. Sci. (Med.)

Russian Federation, Moscow

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