The positive effect of ω-3 polyunsaturated fatty acid supplementation on the cognitive function of children and adolescents with lipid metabolism disorders
- Authors: Zakharova I.N.1, Korchagina I.V.1, Pshenichnikova I.I.1
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Affiliations:
- Russian Medical Academy of Continuous Professional Education
- Issue: No 3 (2024)
- Pages: 260-265
- Section: Articles
- URL: https://pediatria.orscience.ru/2658-6630/article/view/636985
- DOI: https://doi.org/10.26442/26586630.2024.3.202930
- ID: 636985
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Abstract
Aim. To study the effect of ω-3 polyunsaturated fatty acids (PUFAs) on the cognitive functions of children with lipid metabolism disorders of different ages.
Materials and methods. The study included 87 children aged 6 to 17 years who had not previously received ω-3 PUFA supplements. All subjects were tested twice, with an interval of 6 months, to determine the ω-3 erythrocyte index by gas chromatography-mass spectrometry and to study attention span and focusing using the correction task method (Bourdon test). The cohort was randomly divided into two groups: the main group, which included 60 children who received the ω-3 supplements, and the control group, which included 27 children who did not receive any nutritional supplements.
Results. In children of the main group, after receiving the Norwegian fish oil NFO® at 1000 mg for 6 months, an increase in the erythrocyte ω-3 index was observed, while in the control group, it did not change significantly. A statistically significant correlation was found between the adequacy of ω-3 PUFA and the attention span and focusing.
Conclusion. The results of the study showed the effectiveness of ω-3 PUFA supplementation at 1000 mg/day for 6 months and confirmed the positive effect of ω-3 PUFA on the cognitive sphere of children and adolescents. High-quality food supplements with ω-3 PUFAs at 1000 mg/day can be recommended to develop intellection, memory, and attention span and focus in children and adolescents.
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About the authors
Irina N. Zakharova
Russian Medical Academy of Continuous Professional Education
Email: zakharova-rmapo@yandex.ru
ORCID iD: 0000-0003-4200-4598
D. Sci. (Med.), Prof.
Russian Federation, MoscowIuliya V. Korchagina
Russian Medical Academy of Continuous Professional Education
Email: zakharova-rmapo@yandex.ru
Resident
Russian Federation, MoscowIrina I. Pshenichnikova
Russian Medical Academy of Continuous Professional Education
Author for correspondence.
Email: shenichnikovaII@rmapo.ru
ORCID iD: 0000-0002-0058-3803
Cand. Sci. (Med.)
Russian Federation, MoscowReferences
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