STATE OF GASTROINTESTINAL TRACT IN THE JOINT HYPERMOBILITY SYNDROME: FUNCTIONAL DISORDERS OR THE FIRST CALLS OF ORGANICS?

Relevance. Joint hypermobility syndrome (JHS) is the most common variant of connective tissue dysplasia. The syndrome proceeds with changes in the gastrointestinal tract, but the structure and possible causes of this need to be clarified. Aim. Determine the relationship between JHS and the nature of changes in the gastrointestinal tract. Materials and methods. 113 children with joint hypermobility syndrome and 106 without this syndrome were examined. The frequency of functional and organic changes in the groups was determined. Results. Inorganic changes (functional disorders of swallowing, abdominal pain, globe, etc.) prevailed among patients with JHS, but a double gall bladder, cysts of the gall bladder, choledoch were recorded. Among patients with organic lesions (inflammatory diseases of the colon, peptic ulcer, lymphomas, etc.), JHS was recorded very rarely. Conclusion. In children and adolescents with JHS, functional disorders of the gastrointestinal tract predominate. However, already at this age, an organic pathology begins to form, associated with a genetically determined lesion of the connective tissue (diverticulum of the hollow organs).

children, connective tissue, diseases of the gastrointestinal tract