INTRACRANIAL HEMORRHAGES IN LATE HEMORRHAGIC DISEASE OF THE NEWBORNS


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Abstract

The following article presents the thorough analysis of the causes of severe hemorrhagic disorders in full-term children aged 1 -6 months who were hospitalized in the Bashlyaeva Children's City Clinical Hospital (n=41, with an observation period of 5 years). It was found that in 68.3% of cases, the cause of hemorrhagic syndrome was vitamin K deficiency (late hemorrhagic disease of the newborns). It was noted that the main risk factor for the development of vitamin K-deficiency was exclusively breastfeeding (78.6%), whereas biliary atresia, hereditary diseases with intrahepatic cholestasis and malabsorption syndrome were identified as the cause of late hemorrhagic disease of the newborn significantly less often (21.4%). It was found that in 22 of 28 children with a deep deficiency of vitamin K, intracranial hemorrhages occurred. It was noted that in most cases, intracranial hemorrhage was preceded by hemorrhages on the skin and/ or increased bleeding, which were not adequately evaluated, which determined the absence of timely therapy and the progression of hemostasis disorders.

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About the authors

Andrei L. Zaplatnikov

Russian Medical Academy of Continuous Professional Education

Email: zaplatnikov@mail.ru
Moscow, Russia

Oksana V. Brazhnikova

Russian Medical Academy of Continuous Professional Education

Moscow, Russia

Soslan B. Medoev

Bashlyaeva Children City Clinical Hospital

Moscow, Russia

Vladimir V. Nikitin

Bashlyaeva Children City Clinical Hospital

Moscow, Russia

Mikhail S. Efimov

Russian Medical Academy of Continuous Professional Education

Moscow, Russia

Valerii V. Gorev

Russian Medical Academy of Continuous Professional Education

Moscow, Russia

Aleksandr A. Dement'ev

Russian Medical Academy of Continuous Professional Education

Moscow, Russia

Zhuzhuna L. Chabaidze

Russian Medical Academy of Continuous Professional Education

Moscow, Russia

Bronislava A. Ashurova

Bashlyaeva Children City Clinical Hospital

Moscow, Russia

Anna S. Koroleva

Bashlyaeva Children City Clinical Hospital

Moscow, Russia

Iuliia V. Potanina

Bashlyaeva Children City Clinical Hospital

Moscow, Russia

Aleksei A. Trofimov

Bashlyaeva Children City Clinical Hospital

Moscow, Russia

Orest V. Gaevyi

Bashlyaeva Children City Clinical Hospital

Moscow, Russia

Vadim V. Shablia

Bashlyaeva Children City Clinical Hospital

Moscow, Russia

Andrei Iu. Volokhin

Bashlyaeva Children City Clinical Hospital

Moscow, Russia

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